Exfoliamycin
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Antibiotics |
| Catalog number | BBF-00888 |
| CAS | 148084-37-1 |
| Molecular Weight | 434.44 |
| Molecular Formula | C22H26O9 |
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Description
Exfoliamycin is a naphthoquinone antibiotic produced by Streptomyces exfoliamycin Tu 1424. Activity against gram-positive bacteria.
Specification
| Synonyms | 1H-Naphtho(2,3-c)pyran-6,9-dione, 3,4-dihydro-3,10-dihydroxy-3-methyl-8-pentofuranosyl-1-propyl- |
| IUPAC Name | 8-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,10-dihydroxy-3-methyl-1-propyl-1,4-dihydrobenzo[g]isochromene-6,9-dione |
| Canonical SMILES | CCCC1C2=C(C3=C(C=C2CC(O1)(C)O)C(=O)C=C(C3=O)C4C(C(C(O4)CO)O)O)O |
| InChI | InChI=1S/C22H26O9/c1-3-4-13-15-9(7-22(2,29)31-13)5-10-12(24)6-11(17(25)16(10)19(15)27)21-20(28)18(26)14(8-23)30-21/h5-6,13-14,18,20-21,23,26-29H,3-4,7-8H2,1-2H3 |
| InChI Key | VUCLOMKZKFWQMS-UHFFFAOYSA-N |
Properties
| Appearance | Orange-Brown Solid |
| Antibiotic Activity Spectrum | Gram-positive bacteria |
| Melting Point | 90°C |
| Solubility | Soluble in Methanol, methyl ether |
Reference Reading
1. K1115 A, a new anthraquinone that inhibits the binding of activator protein-1 (AP-1) to its recognition sites. II. Taxonomy, fermentation, isolation, physico-chemical properties and structure determination
N Naruse, M Goto, Y Watanabe, T Terasawa, K Dobashi J Antibiot (Tokyo). 1998 Jun;51(6):545-52. doi: 10.7164/antibiotics.51.545.
A new inhibitor of the action of activator protein-1 (AP-1), designated K1115 A, was isolated from the fermentation broth of an actinomycete strain Mer-K1115. K1115 A was determined to be a new anthraquinone, 3,8-dihydroxy-1-propylanthraquinone-2-carboxylic acid, based on spectroscopic analysis, derivatization experiments and biosynthetic studies with 13C-enriched acetic acid. Two co-produced compounds, K1115 B1 and B2, were also isolated and characterized as new members of the naphthopyranomycin and exfoliamycin group.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
