Fistupyrone

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Category Enzyme inhibitors
Catalog number BBF-00931
CAS 315193-05-6
Molecular Weight 182.22
Molecular Formula C10H14O3

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Description

Fistupyrone is a substance produced by Streptornyces sp. TP-A0569. Inhibits the infection of cabbage with Alternaria brassicae.

Specification

IUPAC Name 4-hydroxy-6-(3-methylbutyl)pyran-2-one
Canonical SMILES CC(C)CCC1=CC(=CC(=O)O1)O
InChI InChI=1S/C10H14O3/c1-7(2)3-4-9-5-8(11)6-10(12)13-9/h5-7,11H,3-4H2,1-2H3
InChI Key XBJDHJQNQRRFFL-UHFFFAOYSA-N

Properties

Appearance Colorless Needle Crystal
Antibiotic Activity Spectrum Gram-positive bacteria
Melting Point 73°C
Solubility Soluble in methanol, chloroform, ethyl acetate

Reference Reading

1. Fistupyrone, a novel inhibitor of the infection of Chinese cabbage by Alternaria brassicicola, from Streptomyces sp. TP-A0569
Y Igarashi, M Ogawa, Y Sato, N Saito, R Yoshida, H Kunoh, H Onaka, T Furumai J Antibiot (Tokyo). 2000 Oct;53(10):1117-22. doi: 10.7164/antibiotics.53.1117.
A new microbial metabolite, designated fistupyrone, was isolated from the culture broth of a plant-associated Streptomyces sp. TP-A0569. Fistupyrone inhibited the in vivo infection of the seedlings of Chinese cabbage by Alternaria brassicicola TP-F0423, the cause of Alternaria leaf spot, without any in vitro fungicidal activity.

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