FL-120A
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Antibiotics |
| Catalog number | BBF-03543 |
| CAS | 156429-10-6 |
| Molecular Weight | 524.48 |
| Molecular Formula | C26H24N2O10 |
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Description
FL-120A is produced by the strain of Streptomyces chattanoogensis subsp. taitungessis. It has anti-Gram-positive aerobes and anaerobe activity.
Specification
| Synonyms | FL-120-A; 1,3-Bis(acetyloxy)-11-diazonio-4,9-dihydroxy-2-methyl-2-[(2-methylpropanoyl)oxy]-10-oxo-2,3,4,10-tetrahydro-1H-benzo[b]fluoren-5-olate |
| IUPAC Name | [(1R,2R,3R,4S)-1,3-diacetyloxy-11-diazo-4,9-dihydroxy-2-methyl-5,10-dioxo-3,4-dihydro-1H-benzo[b]fluoren-2-yl] 2-methylpropanoate |
| Canonical SMILES | CC(C)C(=O)OC1(C(C(C2=C(C1OC(=O)C)C(=[N+]=[N-])C3=C2C(=O)C4=C(C3=O)C(=CC=C4)O)O)OC(=O)C)C |
| InChI | InChI=1S/C26H24N2O10/c1-9(2)25(35)38-26(5)23(36-10(3)29)18-16(22(34)24(26)37-11(4)30)15-17(19(18)28-27)21(33)14-12(20(15)32)7-6-8-13(14)31/h6-9,22-24,31,34H,1-5H3/t22-,23+,24+,26+/m0/s1 |
| InChI Key | ZTAVSQVTZIBGBH-POMLREGLSA-N |
Properties
| Appearance | Orange Powder |
| Antibiotic Activity Spectrum | Gram-positive bacteria |
| Melting Point | 62-63°C |
Reference Reading
1. FL-120A-D', new products related to kinamycin from Streptomyces chattanoogensis subsp. taitungensis subsp. nov. II. Isolation and structure determination
J J Young, S N Ho, W M Ju, L R Chang J Antibiot (Tokyo). 1994 Jun;47(6):681-7. doi: 10.7164/antibiotics.47.681.
Six new kinamycin antibiotics have been isolated from the culture filtrate of Streptomyces chattanoogensis. The structures of six related components were determined employing 1D and 2D NMR spectroscopy and mass spectrometry. These structures represent the first reported epoxide kinamycin (2, 3) and propionyl derivative of kinamycin (5), and new isobutyryl derivatives of kinamycin (1, 4, 6).
2. FL-120A-D', new products related to kinamycin from Streptomyces chattanoogensis subsp. taitungensis subsp. nov. I. Taxonomy, fermentation and biological properties
H C Lin, S C Chang, N L Wang, L R Chang J Antibiot (Tokyo). 1994 Jun;47(6):675-80. doi: 10.7164/antibiotics.47.675.
Six new kinamycin antibiotics, designated as FL-120A-D' (1-6) were isolated from the culture filtrate of Streptomyces sp. strain IY2-13. Based on its cultural, physiological, morphological and chemical characteristics, this strain was identified as a new subspecies of Streptomyces chattanoogensis and named S. chattanoogensis subsp. taitungensis. These kinamycins have demonstrated a potent activity against Gram-positive aerobic and anaerobic bacteria.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
