Flavidulol A
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| Category | Antibiotics |
| Catalog number | BBF-00935 |
| CAS | |
| Molecular Weight | 258.35 |
| Molecular Formula | C17H22O2 |
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Description
Flavidulol A is an antibiotic produced by Lactarius flavidula. It has anti-bacterial, anti-fungal activity and immunosuppressive effect.
Specification
| Synonyms | 5,8,9,12-Tetrahydro-4-methoxy-7,11-dimethyl-1-benzocyclodecenol, 9CI |
| IUPAC Name | (6Z,10Z)-4-methoxy-7,11-dimethyl-5,8,9,12-tetrahydrobenzo[10]annulen-1-ol |
| Canonical SMILES | CC1=CCC2=C(C=CC(=C2CC(=CCC1)C)O)OC |
| InChI | InChI=1S/C17H22O2/c1-12-5-4-6-13(2)11-15-14(8-7-12)17(19-3)10-9-16(15)18/h6-7,9-10,18H,4-5,8,11H2,1-3H3/b12-7-,13-6- |
| InChI Key | SZKZGGBNARQQFB-HWBZFXJUSA-N |
Properties
| Appearance | Oil |
| Antibiotic Activity Spectrum | bacteria; fungi |
Reference Reading
1. Identification of immunosuppressive components of a mushroom, Lactarius flavidulus
H Fujimoto, Y Nakayama, M Yamazaki Chem Pharm Bull (Tokyo). 1993 Apr;41(4):654-8. doi: 10.1248/cpb.41.654.
Three metabolites having a suppressive effect on proliferation of mouse lymphocytes stimulated with mitogens such as concanavalin A (Con A) and lipopolysaccharide (LPS) were isolated from a mushroom, Lactarius flavidulus, and identified as geranylphenols, flavidulols A, B and C, respectively, which had previously been isolated from the same mushroom. The IC50 values of flavidulols A, B and C were found to be 8.9, 4.9 and 36.3 micrograms/ml against Con A-induced proliferation of mouse lymphocytes, and 6.7, 3.9 and 28.3 micrograms/ml against LPS-induced proliferation, respectively.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
