Fluostatin B

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Fluostatin B
Category Enzyme inhibitors
Catalog number BBF-01424
CAS 158906-40-2
Molecular Weight 326.30
Molecular Formula C18H14O6

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Description

Fluostatin B is produced by the strain of Streptomyces sp. TA-3391. It inhibits the ability of DPP-III, and with arginyl-arginine-2-naphthalene formamide as the substrate, the IC50 is 24.0μg/mL.

Specification

Synonyms 2,3-Dihydro-3-methyl-1,2,6,7-tetrahydroxy-1H-benzo(a)fluorene-4,11-dione; 1H-Benzo[a]fluorene-4,11-dione,2,3-dihydro-1,2,6,7-tetrahydroxy-3-methyl-(9CI)
IUPAC Name 1,2,6,7-tetrahydroxy-3-methyl-2,3-dihydro-1H-benzo[a]fluorene-4,11-dione
Canonical SMILES CC1C(C(C2=C3C(=C(C=C2C1=O)O)C4=C(C3=O)C=CC=C4O)O)O
InChI InChI=1S/C18H14O6/c1-6-15(21)8-5-10(20)13-11-7(3-2-4-9(11)19)17(23)14(13)12(8)18(24)16(6)22/h2-6,16,18-20,22,24H,1H3
InChI Key PLKATXVLQJQTSA-UHFFFAOYSA-N

Properties

Appearance Orange Clubbed Crystalline
Boiling Point 652°C at 760 mmHg
Melting Point 266-269°C
Density 1.639 g/cm3

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