Folic acid
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category | Raw Materials of Healthcare Products |
Catalog number | BBF-04029 |
CAS | 59-30-3 |
Molecular Weight | 441.40 |
Molecular Formula | C19H19N7O6 |
Purity | >98% |
Catalog Number | Size | Price | Stock | Quantity |
---|---|---|---|---|
BBF-04029 | 500 g | $199 | In stock |
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Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
Folic acid is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, and it also acts as a cofactor in biological reactions involving folate. The combined use of enalapril and folic acid, compared with enalapril alone, significantly reduced the risk of first stroke. High folic acid intakes and MTHFR gene variations seem not to be associated with helping women to achieve pregnancy during or after fertility treatment.
- Specification
- Properties
- Toxicity
- Reference Reading
- Spectrum
- Price Product List
- QC Data
Synonyms | n-4-[(2-amido-4-oxo-1,4-dihydro-6-terene)methylamino]benzoyl-l-glutamic acid |
Shelf Life | As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly |
Storage | Store at -20°C |
IUPAC Name | (2S)-2-[[4-[(2-amino-4-oxo-3H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid |
Canonical SMILES | C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)N=C(N3)N |
InChI | InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1 |
InChI Key | OVBPIULPVIDEAO-LBPRGKRZSA-N |
Appearance | Yellow Powder |
Application | Hematopoietic vitamin |
Melting Point | >195°C |
Density | 1.68 g/cm3 |
Solubility | Soluble in DMSO |
LogP | -2.5 |
Carcinogenicity | No indication of carcinogenicity to humans (not listed by IARC). |
Mechanism Of Toxicity | Folic acid, as it is biochemically inactive, is converted to tetrahydrofolic acid and methyltetrahydrofolate by dihydrofolate reductase. These folic acid congeners are transported across cells by receptor-mediated endocytosis where they are needed to maintain normal erythropoiesis, synthesize purine and thymidylate nucleic acids, interconvert amino acids, methylate tRNA, and generate and use formate. Using vitamin B12 as a cofactor, folic acid can normalize high homocysteine levels by remethylation of homocysteine to methionine via methionine synthetase. |
Toxicity | LD50: 85 mg/kg (Intraperitoneal, Mouse); LD50: 120 mg/kg (Intravenous, Guinea pig); LD50: 239 mg/kg (Intravenous Mouse); LD50: 500 mg/kg (Intravenous, Rat); LD50: 410 mg/kg (Intravenous, Rabbit). |
Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive

Experimental Conditions
Ionization Energy: 70 eV
Chromatography Type: Gas Chromatography Column (GC)
Instrument Type: Single quadrupole, spectrum predicted by CFM-ID(EI)
Mass Resolution: 0.0001 Da
Molecular Formula: C19H19N7O6
Molecular Weight (Monoisotopic Mass): 441.1397 Da
Molecular Weight (Avergae Mass): 441.3975 Da
LC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)

Experimental Conditions
Sample Mass: 1.0 mg
Sample Assessment: Satisfactory
Spectrum Assessment: Satisfactory
Instrument Type: Quattro_QQQ
Collision Energy Level: low
Collision Energy Voltage: 10
Ionization Mode: Positive
Predicted LC-MS/MS Spectrum - 10V, Positive

Experimental Conditions
Collision Energy: 10 eV
Instrument Type: QTOF (generic), spectrum predicted by CFM-ID
Mass Resolution: 0.0001 Da
Molecular Formula: C19H19N7O6
Molecular Weight (Monoisotopic Mass): 441.1397 Da
Molecular Weight (Avergae Mass): 441.3975 Da
Mass Spectrum (Electron Ionization)

1H NMR Spectrum

Experimental Conditions
Sample Assessment: Excellent
Spectrum Assessment: Excellent
Instrument Type: Varian
Nucleus: 1H
Frequency: 500 MHz
Sample pH: 7.00
Sample Temperature: 25.0 Celsius
Chemical Shift Reference: DSS
[1H,13C] 2D NMR Spectrum

Experimental Conditions
Solvent: Water
Sample Mass: 22.1 mg
Sample Assessment: Excellent
Spectrum Assessment: Excellent
Instrument Type: Bruker
Nucleus X: 1H
Nucleus Y: 13C
Frequency: 600 MHz
Sample pH: 7.00
Sample Temperature: 25.0 Celsius
Chemical Shift Reference: DSS
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
