Formobactin
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| Category | Others |
| Catalog number | BBF-01433 |
| CAS | |
| Molecular Weight | 743.88 |
| Molecular Formula | C38H57N5O10 |
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Description
It is produced by the strain of Norcadia sp. ND20. Formobactin can inhibit lipid peroxidation in rat brain homogenates with IC50 of 0.65 μmol/L.
Specification
| IUPAC Name | [1-[(1-hydroxy-2-oxoazepan-3-yl)amino]-2,2-dimethyl-1-oxododecan-3-yl] (2S)-6-[formyl(hydroxy)amino]-2-[[2-(2-hydroxyphenyl)-5-methyl-1,3-oxazole-4-carbonyl]amino]hexanoate |
| Canonical SMILES | CCCCCCCCCC(C(C)(C)C(=O)NC1CCCCN(C1=O)O)OC(=O)C(CCCCN(C=O)O)NC(=O)C2=C(OC(=N2)C3=CC=CC=C3O)C |
| InChI | InChI=1S/C38H57N5O10/c1-5-6-7-8-9-10-11-22-31(38(3,4)37(49)40-28-19-15-17-24-43(51)35(28)47)53-36(48)29(20-14-16-23-42(50)25-44)39-33(46)32-26(2)52-34(41-32)27-18-12-13-21-30(27)45/h12-13,18,21,25,28-29,31,45,50-51H,5-11,14-17,19-20,22-24H2,1-4H3,(H,39,46)(H,40,49)/t28?,29-,31?/m0/s1 |
| InChI Key | ZZBSPTCNZDTZBR-QGXZNONUSA-N |
Properties
| Appearance | White Powder |
| Melting Point | 68-72°C |
Reference Reading
1. Formobactin, a novel free radical scavenging and neuronal cell protecting substance from Nocardia sp
Y Murakami, S Kato, M Nakajima, M Matsuoka, H Kawai, K Shin-Ya, H Seto J Antibiot (Tokyo). 1996 Sep;49(9):839-45. doi: 10.7164/antibiotics.49.839.
Formobactin, a new free radical scavenger, was isolated from the culture of Nocardia sp. strain ND20. The structure of formobactin was determined to be a member of the nocobactin group antibiotics. Formobactin inhibited lipid peroxidation in rat brain homogenate. Formobactin also showed the activity to suppress L-glutamate toxicity in neuronal hybridoma N18-RE-105 cells.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
