FR 900109

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Category Antibiotics
Catalog number BBF-03559
CAS 83512-61-2
Molecular Weight 500.54
Molecular Formula C27H32O9

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Description

It is produced by the strain of Streptomyces prunicolor. FR 900109 has anti-gram-positive bacteria activity.

Specification

Synonyms Antibiotic FR900109; FR900109
IUPAC Name (2R,3S,6S,8R,11S,12S,13R)-1-[(3S)-3-acetyloxy-5-methylidene-2,4-dioxooxolan-3-yl]-13-[(E)-but-2-en-2-yl]-2,12-dimethyl-14,15-dioxatetracyclo[10.2.1.02,11.03,8]pentadec-9-ene-6-carboxylic acid
Canonical SMILES CC=C(C)C1C2(C3C=CC4CC(CCC4C3(C(O1)(O2)C5(C(=O)C(=C)OC5=O)OC(=O)C)C)C(=O)O)C
InChI InChI=1S/C27H32O9/c1-7-13(2)21-25(6)19-11-9-16-12-17(22(30)31)8-10-18(16)24(19,5)27(35-21,36-25)26(34-15(4)28)20(29)14(3)33-23(26)32/h7,9,11,16-19,21H,3,8,10,12H2,1-2,4-6H3,(H,30,31)/b13-7+/t16-,17-,18-,19-,21+,24+,25-,26+,27?/m0/s1
InChI Key LEYIVANMSUUCTR-DIHUVOILSA-N

Properties

Appearance Colorless Crystalline
Antibiotic Activity Spectrum Gram-positive bacteria
Boiling Point 657.7°C at 760 mmHg
Melting Point 263-264°C
Density 1.34 g/cm3
Solubility Soluble in Acetone, Methanol (Slightly)

Reference Reading

1. Studies on a new antibiotic FR-900109. 1. Taxonomy, isolation and characterization
M Yamashita, M Iwami, K Ikushima, T Komori, H Aoki, H Imanaka J Antibiot (Tokyo). 1983 Sep;36(9):1123-8. doi: 10.7164/antibiotics.36.1123.
FR-900109 is a new antibiotic obtained from fermentation broth of a streptomyces which was identified as Streptomyces prunicolor. Its elementary analysis and mass spectroscopic measurement suggest that the molecular formula is C27H32O9. It has an ultraviolet absorption maximum at 254 nm. The antibiotic is active against Gram-positive bacteria. Acute toxicity in mice is very low.

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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