FR 900403

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FR 900403
Category Antibiotics
Catalog number BBF-03564
CAS 131206-83-2
Molecular Weight 393.40
Molecular Formula C16H23N7O5

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Description

FR 900403 is a nucleoside antibiotic originally isolated from Kernia sp. F-19849. It had anti-Candida activity, and the MIC against Candida albicans FP663 was 0.4 μg/mL.

Specification

Synonyms FR900403; beta-D-Ribofuranuronic acid, 3-((2-amino-3-methyl-1-oxopentyl)amino)-1-(6-amino-9H-purin-9-yl)-1,3-dideoxy-
IUPAC Name 3-[(2-amino-3-methylpentanoyl)amino]-5-(6-aminopurin-9-yl)-4-hydroxyoxolane-2-carboxylic acid
Canonical SMILES CCC(C)C(C(=O)NC1C(C(OC1C(=O)O)N2C=NC3=C(N=CN=C32)N)O)N
InChI InChI=1S/C16H23N7O5/c1-3-6(2)7(17)14(25)22-8-10(24)15(28-11(8)16(26)27)23-5-21-9-12(18)19-4-20-13(9)23/h4-8,10-11,15,24H,3,17H2,1-2H3,(H,22,25)(H,26,27)(H2,18,19,20)
InChI Key UGBUVVBCVYWCSO-UHFFFAOYSA-N

Properties

Appearance Amorphous Powder
Antibiotic Activity Spectrum fungi
Melting Point 218-229°C
Density 1.77±0.1 g/cm3
Solubility Soluble in Water, Methanol (Slightly)

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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