Fulvoferruginin
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| Category | Antibiotics |
| Catalog number | BBF-01450 |
| CAS | |
| Molecular Weight | 246.30 |
| Molecular Formula | C15H18O3 |
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Description
Fulvoferruginin is produced by the strain of Marasmius fuloferrugineus. It showed cytotoxicity and antifungal activity, especially to Paecilomyces varioti with MIC of 1-5 μg/mL.
Specification
| IUPAC Name | (1R,4R,8S,13S)-4-hydroxy-1,10-dimethyl-5-methylidene-7-oxatricyclo[6.4.1.04,13]trideca-9,11-dien-6-one |
| Canonical SMILES | CC1=CC2C3C(CCC3(C(=C)C(=O)O2)O)(C=C1)C |
| InChI | InChI=1S/C15H18O3/c1-9-4-5-14(3)6-7-15(17)10(2)13(16)18-11(8-9)12(14)15/h4-5,8,11-12,17H,2,6-7H2,1,3H3/t11-,12+,14-,15-/m0/s1 |
| InChI Key | CGOCLPVLXNAUEN-NEBZKDRISA-N |
Properties
| Appearance | Crystalline |
| Antibiotic Activity Spectrum | fungi |
| Melting Point | 127°C |
Reference Reading
1. Analogs of the carotane antibiotic fulvoferruginin from submerged cultures of a Thai Marasmius sp
Birthe Sandargo, Leon Kaysan, Rémy B Teponno, Christian Richter, Benjarong Thongbai, Frank Surup, Marc Stadler Beilstein J Org Chem. 2021 Jun 4;17:1385-1391. doi: 10.3762/bjoc.17.97. eCollection 2021.
A recent find of a Marasmius species in Northern Thailand led to the isolation of five unprecedented derivatives of the carotane antibiotic fulvoferruginin (1), fulvoferruginins B-F (2-6). The structures of these sesquiterpenoids were elucidated using HRESIMS, 1D and 2D NMR, as well as CD spectroscopy. Assessing the bioactivity, fulvoferruginin emerged as a potent cytotoxic agent of potential pharmaceutical interest.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
