Furaquinocin C
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| Category | Antibiotics |
| Catalog number | BBF-01462 |
| CAS | 134984-98-8 |
| Molecular Weight | 370.44 |
| Molecular Formula | C22H26O5 |
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Description
Furaquinocin C is originally isolated from Streptomyces sp. KO-3988. It can kill HeLa S3 and B16 melanoma cells, but has no antibacterial activity.
Specification
| Synonyms | Furaquinocin C3; 4-hydroxy-7-methoxy-2,3,8-trimethyl-3-(4-methylpent-3-en-1-yl)-2,3-dihydronaphtho[1,2-b]furan-6,9-dione; Naphtho(1,2-b)furan-6,9-dione, 2,3-dihydro-4-hydroxy-7-methoxy-2,3,8-trimethyl-3-(4-methyl-3-pentenyl)- |
| IUPAC Name | 4-hydroxy-7-methoxy-2,3,8-trimethyl-3-(4-methylpent-3-enyl)-2H-benzo[g][1]benzofuran-6,9-dione |
| Canonical SMILES | CC1C(C2=C(C=C3C(=C2O1)C(=O)C(=C(C3=O)OC)C)O)(C)CCC=C(C)C |
| InChI | InChI=1S/C22H26O5/c1-11(2)8-7-9-22(5)13(4)27-21-16-14(10-15(23)17(21)22)19(25)20(26-6)12(3)18(16)24/h8,10,13,23H,7,9H2,1-6H3 |
| InChI Key | GDSPWZDWUUGKIM-UHFFFAOYSA-N |
Properties
| Appearance | Yellow Acicular Crystalline |
| Antibiotic Activity Spectrum | neoplastics (Tumor) |
| Boiling Point | 567.1°C at 760 mmHg |
| Melting Point | 213-215°C |
| Density | 1.22 g/cm3 |
Reference Reading
1. Novel antibiotics, furaquinocins C, D, E, F, G and H
M Ishibashi, S Funayama, Y Anraku, K Komiyama, S Omura J Antibiot (Tokyo). 1991 Apr;44(4):390-5. doi: 10.7164/antibiotics.44.390.
Furaquinocins C, D, E, F, G and H, congeners of furaquinocins A and B, were isolated from the culture broth of Streptomyces sp. KO-3988 and their structures have been determined on the basis of their spectroscopical and chemical properties. These antibiotics showed cytocidal activities against HeLa S3 and B16 melanoma cells in vitro.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
