gamma-Glutamylarginine
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Category | Others |
Catalog number | BBF-05130 |
CAS | 31106-03-3 |
Molecular Weight | 303.31 |
Molecular Formula | C11H21N5O5 |
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Specification
Synonyms | Glu-Arg; L-Glutamyl-L-Arginine |
Sequence | H-Glu-Arg-OH |
IUPAC Name | (2S)-2-amino-5-[[(1S)-1-carboxy-4-(diaminomethylideneamino)butyl]amino]-5-oxopentanoic acid |
Canonical SMILES | C(CC(C(=O)O)NC(=O)C(CCC(=O)O)N)CN=C(N)N |
InChI | InChI=1S/C11H21N5O5/c12-6(3-4-8(17)18)9(19)16-7(10(20)21)2-1-5-15-11(13)14/h6-7H,1-5,12H2,(H,16,19)(H,17,18)(H,20,21)(H4,13,14,15)/t6-,7-/m0/s1 |
InChI Key | MPZWMIIOPAPAKE-BQBZGAKWSA-N |
Reference Reading
1. Isolation and characterization of a group of oligopeptides related to oxidized glutathione from the root of Panax ginseng
Z K Chen, C X Fan, Y H Ye, L Yang, Q Jiang, Q Y Xing J Pept Res. 1998 Aug;52(2):137-42. doi: 10.1111/j.1399-3011.1998.tb01368.x.
Six gamma-glutamyl oligopeptides were isolated for the first time from aqueous methanol extracts of Panax ginseng root by using column chromatography on ion-exchange resin, gel filtration and reverse-phase high-performance liquid chromatography. Their structures had been established with the methods of amino acid analysis, N-terminal, C-terminal determination and double-coupling sequence analysis. They were: P-I (N-gamma-glutamylcystinyl-bis-glycine), P-ll (gamma-glutamylcysteinylglycine disulfide, oxidized glutathione), P-III (N,N'-bis-gamma-glutamylcystinylglycine), P-IV (gamma-glutamylcysteinylglycinamide disulfide), P-V (N-gamma-glutamylglycylcysteine disulfide), P-VI(gammaglutamylarginine); five of them are related to oxidized glutathione. The structures were further confirmed by the chemical synthesis. As far as we know, P-V (N-gamma-glutamylglycylcysteine disulfide) is a new biologically active peptide which exhibits somnogenic effect and is more potent than that of P-II.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳