Glisoprenin E
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| Category | Enzyme inhibitors |
| Catalog number | BBF-01257 |
| CAS | |
| Molecular Weight | 771.16 |
| Molecular Formula | C45H86O9 |
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Description
It is produced by the strain of Gliocladium roseum HA190-95. It is a cholesterol acyltransferase (ACAT) inhibitor, and it can inhibit the formation of Appressorium on the hydrophobic surface of Magnaporthegrisea.
Specification
| IUPAC Name | (2E,10E,14E)-3,7,11,15,19,23,27,31,35-nonamethylhexatriaconta-2,10,14-triene-1,6,7,19,23,27,31,34,35-nonol |
| Canonical SMILES | CC(=CCCC(=CCCC(C)(C(CCC(=CCO)C)O)O)C)CCCC(C)(CCCC(C)(CCCC(C)(CCCC(C)(CCC(C(C)(C)O)O)O)O)O)O |
| InChI | InChI=1S/C45H86O9/c1-35(17-11-18-36(2)20-13-32-45(10,54)39(48)22-21-37(3)24-34-46)19-12-25-41(6,50)26-14-27-42(7,51)28-15-29-43(8,52)30-16-31-44(9,53)33-23-38(47)40(4,5)49/h17,20,24,38-39,46-54H,11-16,18-19,21-23,25-34H2,1-10H3/b35-17+,36-20+,37-24+ |
| InChI Key | FXTQBFBSROLPRX-FHAYICFZSA-N |
Properties
| Appearance | Colorless Oily Matter |
| Antibiotic Activity Spectrum | Fungi |
| Solubility | Soluble in Methanol, Chloroform |
Reference Reading
1. Glisoprenins C, D and E, new inhibitors of appressorium formation in Magnaporthe grisea, from cultures of Gliocladium roseum. 1. Production and biological activities
E Thines, F Eilbert, H Anke, O Sterner J Antibiot (Tokyo). 1998 Feb;51(2):117-22. doi: 10.7164/antibiotics.51.117.
Glisoprenins C, D, and E, new glisoprenin derivatives, were isolated together with glisoprenin A from submerged cultures of the deuteromycete Gliocladium roseum HA190-95. All glisoprenins inhibited appressorium formation in Magnaporthe grisea on inductive (hydrophobic) surfaces. The compounds exhibited moderate cytotoxic, but no antifungal, antibacterial or phytotoxic activities.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
