Griseofulvin
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category | Antibiotics |
Catalog number | BBF-01806 |
CAS | 126-07-8 |
Molecular Weight | 352.77 |
Molecular Formula | C17H17ClO6 |
Purity | >98% |
Catalog Number | Size | Price | Stock | Quantity |
---|---|---|---|---|
BBF-01806 | 50 g | $199 | In stock |
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Add to cartCapabilities & Facilities
Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
It is produced by the strain of Penicillum griseofulvum. It can inhibit the strains of ClassZygomycetes, Ascomycetes and Deuteromycetes (MIC is 1-20 μg/mL), It can also inhibit the crimping of the spore tube of garlic rot grape (MIC is 1 μg/mL). It has obvious inhibitory effect on metaphase mitosis of bone marrow, small intestine and Walker 256 cancer cells.
- Specification
- Properties
- Toxicity
- Reference Reading
- Spectrum
- Price Product List
- QC Data
Synonyms | Curling factor; Fulvicin; Gris PEG; GrisPEG; Gris-PEG; Grisactin; Amudane; 7-Chloro-2',4,6-trimethoxy-6'beta-methylspiro(benzofuran-2(3H), 1'-(2)cyclohexene)-3,4'-dione; (2S-trans)-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2(3H), 1'-(2)cyclohexene)-3,4'-dione |
Storage | 2-8 °C |
IUPAC Name | (2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione |
Canonical SMILES | CC1CC(=O)C=C(C12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC |
InChI | InChI=1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1 |
InChI Key | DDUHZTYCFQRHIY-RBHXEPJQSA-N |
Source | Penicillium sp. |
Appearance | ColoRed diamond or Acicular Crystal |
Antibiotic Activity Spectrum | Neoplastics (Tumor); Fungi |
Boiling Point | 469.04 °C (Predicted) |
Melting Point | 225-226 °C |
Density | 1.2579 g/cm3 (Predicted) |
Solubility | Slightly soluble in Chloroform, Ethyl Acetate, Acetone, Benzene, Dioxane |
LogP | 2.18 |
Carcinogenicity | 2B, possibly carcinogenic to humans. |
Mechanism Of Toxicity | Griseofulvin is fungistatic, however the exact mechanism by which it inhibits the growth of dermatophytes is not clear. It is thought to inhibit fungal cell mitosis and nuclear acid synthesis. It also binds to and interferes with the function of spindle and cytoplasmic microtubules by binding to alpha and beta tubulin. It binds to keratin in human cells, then once it reaches the fungal site of action, it binds to fungal microtubes thus altering the fungal process of mitosis. |
Spectrum
Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive

Experimental Conditions
Ionization Energy: 70 eV
Chromatography Type: Gas Chromatography Column (GC)
Instrument Type: Single quadrupole, spectrum predicted by CFM-ID(EI)
Mass Resolution: 0.0001 Da
Molecular Formula: C17H17ClO6
Molecular Weight (Monoisotopic Mass): 352.0714 Da
Molecular Weight (Avergae Mass): 352.766 Da
LC-MS/MS Spectrum - LC-ESI-qTof , Positive

Experimental Conditions
Ionization Mode: Positive
Predicted LC-MS/MS Spectrum - 10V, Positive

Experimental Conditions
Collision Energy: 10 eV
Instrument Type: QTOF (generic), spectrum predicted by CFM-ID
Mass Resolution: 0.0001 Da
Molecular Formula: C17H17ClO6
Molecular Weight (Monoisotopic Mass): 352.0714 Da
Molecular Weight (Avergae Mass): 352.766 Da
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
