Get A Quote

Griseolic acid B

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Griseolic acid B
Category Enzyme inhibitors
Catalog number BBF-01286
CAS 98890-01-8
Molecular Weight 363.28
Molecular Formula C14H13N5O7

Online Inquiry

Capabilities & Facilities

Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

It is produced by the strain of Streptomyces griseoaurantiacus SANK43894. It has the activity of inhibiting cyclic adenosine monophosphate (cAMP) phosphodiesterase [EC 3.1.4.17] with IC50 0.16 X 10-6 mol/L (Extracted from rat brain).

  • Specification
  • Properties
  • Reference Reading
  • Price Product List
Synonyms (2R,5R,6R,6aS)-5-(6-amino-9H-purin-9-yl)-2-(carboxymethyl)-6-hydroxy-2,5,6,6a-tetrahydrofuro[3,2-b]furan-2-carboxylic acid; Deoxygriseolic Acid; 1-(6-Amino-9H-purin-9-yl)-3,6-anhydro-6-C-carboxy-1,5,7-trideoxy-β-D-ribo-4-octenofuranuronic acid; 7'-Desoxygriseolic acid
IUPAC Name (2R,3R,3aS,5R)-2-(6-aminopurin-9-yl)-5-(carboxymethyl)-3-hydroxy-3,3a-dihydro-2H-furo[3,2-b]furan-5-carboxylic acid
Canonical SMILES C1=C2C(C(C(O2)N3C=NC4=C(N=CN=C43)N)O)OC1(CC(=O)O)C(=O)O
InChI InChI=1S/C14H13N5O7/c15-10-7-11(17-3-16-10)19(4-18-7)12-8(22)9-5(25-12)1-14(26-9,13(23)24)2-6(20)21/h1,3-4,8-9,12,22H,2H2,(H,20,21)(H,23,24)(H2,15,16,17)/t8-,9-,12-,14+/m1/s1
InChI Key WRHIKWNGCJVUOW-MGGABWITSA-N
Appearance White Powder
Boiling Point 889.2 °C at 760 mmHg
Melting Point 160 °C
Density 2.13 g/cm3
Solubility Soluble in Water, DMSO
1. Synthesis of griseolic acid B by pi-face-dependent radical cyclization
S Knapp, M R Madduru, Z Lu, G J Morriello, T J Emge, G A Doss Org Lett. 2001 Nov 1;3(22):3583-5. doi: 10.1021/ol0167210.
[reaction: see text]. Radical cyclization of 6 affords the bicyclic vinyl ether 9 with the appropriate stereochemistry for elaboration (seven steps) to griseolic acid B (1).

Bio Calculators

Stock concentration: *
Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
g

Recently viewed products

Online Inquiry

Copyright © 2025 BOC Sciences. All rights reserved.

cartIcon
Inquiry Basket