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Guamecycline

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Guamecycline
Category Antibiotics
Catalog number BBF-01808
CAS 16545-11-2
Molecular Weight 626.67
Molecular Formula C29H38N8O8
Purity ≥95%

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Capabilities & Facilities

Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

It is produced by the strain of Streptomyces sp. NK11687. It is a semisynthetic tetracycline. The antibacterial spectrum and antibacterial activity are the same as tetracycline, it is characterized by stronger affinity to bronchial and lung tissue than tetracycline, blood drug concentration is higher than tetracycline and lasting.

  • Specification
  • Properties
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Synonyms Tetrabiguanide; Xanthomycin A; Xantomicina; Guamecyclinum; N-((4-(((Aminoiminomethyl)amino)iminomethyl)-1-piperazinyl)methyl)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide (4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha))-; N,N-Diethyleneiminobiguanidomethyltetracycline
IUPAC Name (4S,4aS,5aS,6S,12aR)-N-[[4-[N-(diaminomethylidene)carbamimidoyl]piperazin-1-yl]methyl]-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
Canonical SMILES CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)NCN5CCN(CC5)C(=N)N=C(N)N)N(C)C)O
InChI InChI=1S/C29H38N8O8/c1-28(44)13-5-4-6-16(38)17(13)21(39)18-14(28)11-15-20(35(2)3)22(40)19(24(42)29(15,45)23(18)41)25(43)33-12-36-7-9-37(10-8-36)27(32)34-26(30)31/h4-6,14-15,20,38-39,42,44-45H,7-12H2,1-3H3,(H,33,43)(H5,30,31,32,34)/t14-,15-,20-,28+,29-/m0/s1
InChI Key FAMUIRDLAWWMCQ-AQFAATAFSA-N
Boiling Point 849.9 °C at 760 mmHg
Density 1.67±0.1 g/cm3 (Predicted)
Solubility Soluble in Water

Bio Calculators

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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