Guamecycline dihydrochloride
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Category | Antibiotics |
Catalog number | BBF-01296 |
CAS | 13040-98-7 |
Molecular Weight | 699.59 |
Molecular Formula | C29H38N8O8.2HCl |
Purity | ≥95% |
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Description
It is produced by the strain of Streptomyces sp. NK11687. It is a semisynthetic tetracycline. The antibacterial spectrum and antibacterial activity are the same as tetracycline, it is characterized by stronger affinity to bronchial and lung tissue than tetracycline, blood drug concentration is higher than tetracycline and lasting.
Specification
Related CAS | 16545-11-2 (free base) |
Synonyms | guamecycline dihydrochloride; Xanthomycin a, dihydrochloride; Xanthocycline dihydrochloride; Guamecycline 2HCl; 2-Naphthacenecarboxamide, N-((4-(((aminoiminomethyl)amino)iminomethyl)-1-piperazinyl)methyl)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, dihydrochloride, (4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha))- |
IUPAC Name | (4S,4aS,5aS,6S,12aR)-N-[[4-[N-(diaminomethylidene)carbamimidoyl]piperazin-1-yl]methyl]-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;dihydrochloride |
Canonical SMILES | CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)NCN5CCN(CC5)C(=N)N=C(N)N)N(C)C)O.Cl.Cl |
InChI | InChI=1S/C29H38N8O8.2ClH/c1-28(44)13-5-4-6-16(38)17(13)21(39)18-14(28)11-15-20(35(2)3)22(40)19(24(42)29(15,45)23(18)41)25(43)33-12-36-7-9-37(10-8-36)27(32)34-26(30)31;;/h4-6,14-15,20,38-39,42,44-45H,7-12H2,1-3H3,(H,33,43)(H5,30,31,32,34);2*1H/t14-,15-,20-,28+,29-;;/m0./s1 |
InChI Key | YWILDZMVBIMXID-KGHBUBBXSA-N |
Properties
Appearance | Yellow Crystalline Powder |
Solubility | Soluble in Water |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2