Haliangicin C

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Category Antibiotics
Catalog number BBF-01306
CAS
Molecular Weight 376.49
Molecular Formula C22H32O5

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Description

It is produced by the strain of Haliangium luteum AJ-13395, H. ochraceum. It is similar to amphotericin B with anti-filamentous fungi activity (MIC 0.1-12.5 μg/mL), and it also has effect on oomycetes, but has no antibacterial activity. The antifungal activity of cis-trans isomer is similar, the activity of Haliangicin B and C is weaker than Haliangicin A, and the activity of Haliangicin D is weakest.

Specification

IUPAC Name methyl (2E,4E,6Z,8E,10S)-11-[(2S,3S)-3-ethenyl-2-methyloxiran-2-yl]-3,4-dimethoxy-6,9,10-trimethylundeca-2,4,6,8-tetraenoate
Canonical SMILES CC(CC1(C(O1)C=C)C)C(=CC=C(C)C=C(C(=CC(=O)OC)OC)OC)C
InChI InChI=1S/C22H32O5/c1-9-20-22(5,27-20)14-17(4)16(3)11-10-15(2)12-18(24-6)19(25-7)13-21(23)26-8/h9-13,17,20H,1,14H2,2-8H3/b15-10-,16-11+,18-12+,19-13+/t17-,20-,22-/m0/s1
InChI Key XIKGETOZQXNXHV-XPOASIRBSA-N

Properties

Appearance Pale Yellow Oily Matter
Antibiotic Activity Spectrum Fungi
Solubility Soluble in Methanol

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It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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