Himalomycin A

Himalomycin A

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Category Antibiotics
Catalog number BBF-00961
CAS 701915-10-8
Molecular Weight 824.87
Molecular Formula C43H52O16

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Description

Himalomycin A is an anthraquinone antibiotic isolated from the fermentation broth of Streptomyces B6921. It has strong activity against Staphylococcus aureus, Escherichia coli and Streptomyces vuridochromogenes.

Properties

Appearance Orange Solid
Antibiotic Activity Spectrum Gram-positive bacteria; Gram-negative bacteria

Reference Reading

1. Himalomycin A and B: isolation and structure elucidation of new fridamycin type antibiotics from a marine Streptomyces isolate
Rajendra P Maskey, Elisabeth Helmke, Hartmut Laatsch J Antibiot (Tokyo). 2003 Nov;56(11):942-9. doi: 10.7164/antibiotics.56.942.
In our screening of marine Streptomycetes for bioactive compounds, in addition to the known metabolites rabelomycin (1), fridamycin D (2b), N-benzylacetamide and N-(2'-phenylethyl)acetamide, two new anthracycline antibiotics designated as himalomycin A (2c) and B (2d) were isolated from the culture broth of the marine Streptomyces sp. isolate B6921. The structure of the new antibiotics was determined by comparison of the NMR data with those of fridamycin D (2b) and by detailed interpretation of mass, 1D and 2D NMR spectra.

Bio Calculators

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
g

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