Himalomycin A

Name: Himalomycin A
Brand: BOC Sciences
Rating: 5 (1 reviews)

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category	Antibiotics
Catalog number	BBF-00961
CAS	701915-10-8
Molecular Weight	824.87
Molecular Formula	C43H52O16

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Capabilities & Facilities

Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

Himalomycin A is an anthraquinone antibiotic isolated from the fermentation broth of Streptomyces B6921. It has strong activity against Staphylococcus aureus, Escherichia coli and Streptomyces vuridochromogenes.

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Appearance	Orange Solid
Antibiotic Activity Spectrum	Gram-positive bacteria; Gram-negative bacteria

1. Himalomycin A and B: isolation and structure elucidation of new fridamycin type antibiotics from a marine Streptomyces isolate

Rajendra P Maskey, Elisabeth Helmke, Hartmut Laatsch J Antibiot (Tokyo). 2003 Nov;56(11):942-9. doi: 10.7164/antibiotics.56.942.

In our screening of marine Streptomycetes for bioactive compounds, in addition to the known metabolites rabelomycin (1), fridamycin D (2b), N-benzylacetamide and N-(2'-phenylethyl)acetamide, two new anthracycline antibiotics designated as himalomycin A (2c) and B (2d) were isolated from the culture broth of the marine Streptomyces sp. isolate B6921. The structure of the new antibiotics was determined by comparison of the NMR data with those of fridamycin D (2b) and by detailed interpretation of mass, 1D and 2D NMR spectra.

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It is commonly abbreviated as: C₁V₁ = C₂V₂

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Himalomycin A

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