Homomycin
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| Category | Others |
| Catalog number | BBF-00969 |
| CAS | 6379-56-2 |
| Molecular Weight | 511.48 |
| Molecular Formula | C23H29NO12 |
| Purity | ≥95% |
Ordering Information
| Catalog Number | Size | Price | Stock | Quantity |
|---|---|---|---|---|
| BBF-00969 | 25 mg | $399 | In stock |
Online Inquiry
Add to cartDescription
Homomycin is an aromatic glycoside produced by Streptomyces noboritoensis. It has anti-gram-positive bacteria and mycobacterial activity, and also has an effect on mycoplasma, leptospira, intestinal amoeba, tapeworm, and roundworm.
Specification
| Synonyms | 5-Deoxy-5-[[(2E)-3-[4-[(6-deoxy-β-D-arabino-hexofuranos-5-ulos-1-yl)oxy]-3-hydroxyphenyl]-2-methyl-1-oxo-2-propen-1-yl]amino]-1,2-O-methylene-D-neo-inositol; (E)-5-Deoxy-5-[[3-[4-[(6-deoxy-β-D-arabino-hexofuranos-5-ulos-1-yl)oxy]-3-hydroxyphenyl]-2-methyl-1-oxo-2-propenyl]amino]-1,2-O-methylene-D-neo-inositol; Hygromycin A; Hygromycin; (-)-Hygromycin A; 1703-18B; Antibiotic WS 1627B; Totomycin; (E)-3-(4-(((2S,3S,4S,5S)-5-Acetyl-3,4-dihydroxytetrahydrofuran-2-yl)oxy)-3-hydroxyphenyl)-2-methyl-N-((3aS,4R,5R,6S,7R,7aR)-4,6,7-trihydroxyhexahydrobenzo[d][1,3]dioxol-5-yl)acrylamide |
| Storage | Store at -20°C |
| IUPAC Name | (E)-N-[(3aS,4R,5R,6S,7R,7aR)-4,6,7-trihydroxy-3a,4,5,6,7,7a-hexahydro-1,3-benzodioxol-5-yl]-3-[4-[(2S,3S,4S,5S)-5-acetyl-3,4-dihydroxyoxolan-2-yl]oxy-3-hydroxyphenyl]-2-methylprop-2-enamide |
| Canonical SMILES | CC(=CC1=CC(=C(C=C1)OC2C(C(C(O2)C(=O)C)O)O)O)C(=O)NC3C(C(C4C(C3O)OCO4)O)O |
| InChI | InChI=1S/C23H29NO12/c1-8(22(32)24-13-14(27)16(29)21-20(15(13)28)33-7-34-21)5-10-3-4-12(11(26)6-10)35-23-18(31)17(30)19(36-23)9(2)25/h3-6,13-21,23,26-31H,7H2,1-2H3,(H,24,32)/b8-5+/t13-,14+,15-,16-,17+,18+,19-,20+,21-,23-/m1/s1 |
| InChI Key | YQYJSBFKSSDGFO-IIHALWDASA-N |
Properties
| Appearance | White Powder |
| Antibiotic Activity Spectrum | Gram-positive bacteria; mycobacteria; mycoplasma; parasites |
| Boiling Point | 925.5±65.0 °C at 760 mmHg |
| Melting Point | 110-112°C (dec.) |
| Density | 1.6±0.1 g/cm3 |
| Solubility | Soluble in DMF, DMSO, Ethanol |
Reference Reading
1. [Effect of hepatocyte growth factor gene transfection on biological features of lymphoma cells]
Dong Cen, Hang Zhao, Rong-rong Shen, Shi-xuan Hua, Jian-xin Lu, Ren-zhi Pei, Zhi-guang Tu Zhejiang Da Xue Xue Bao Yi Xue Ban. 2010 Jul;39(4):378-85. doi: 10.3785/j.issn.1008-9292.2010.04.007.
Objective: To investigate the biological effect of hepatocyte growth factor (HGF) on HGF gene-transfected Raji cells. Methods: Total RNA was extracted from human hepatic tissue, HGF gene cDNA was amplified by RT-PCR, and then cloned into vector pVITRO2-mcs to construct recombinant eukaryotic expression vector pVITRO2-mcs-HGF. The recombinant vector was transfected to Raji cells, and the stably transfected cells were selected by homomycin B in serial passages, and confirmed by real-time fluorescent quantitative PCR, ELISA, immunocytohistochemistry. The biological features of transfected Raji cells were evaluated by semisolid culture. Results: RT-PCR results showed that Raji cells were transfected successfully with recombinant eukaryotic expression vector pVITRO2-mcs-HGF. HGF mRNA and protein were expressed successfully in Raji cells. Expression of HGF gene enhanced proliferation, metastasis and invasion of Raji cells. Conclusion: HGF gene has been cloned and recombined to construct recombinant eukaryotic expression vector pVITRO2-mcs-HGF successfully. Transfected HGF may change the biological features of Raji cells.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
