Icotinib hydrochloride
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Category | Enzyme inhibitors |
Catalog number | BBF-04036 |
CAS | 1204313-51-8 |
Molecular Weight | 427.88 |
Molecular Formula | C22H22ClN3O4 |
Purity | >98% |
Catalog Number | Size | Price | Stock | Quantity |
---|---|---|---|---|
BBF-04036 | 300 mg | $299 | In stock |
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Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
Icotinib Hydrochloride is a quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), which is upregulated in a variety of cancer cell types. Icotinib supresses the cancer cell proliferation via EGFR tyrosine kinase inhibition.
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- Properties
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Related CAS | 610798-31-7 (free base) |
Synonyms | Icotinib HCl; BPI-2009; BPI 2009; BPI2009 |
Storage | Store at -20°C |
IUPAC Name | N-(3-ethynylphenyl)-2,5,8,11-tetraoxa-15,17-diazatricyclo[10.8.0.014,19]icosa-1(12),13,15,17,19-pentaen-18-amine;hydrochloride |
Canonical SMILES | C#CC1=CC(=CC=C1)NC2=NC=NC3=CC4=C(C=C32)OCCOCCOCCO4.Cl |
InChI | InChI=1S/C22H21N3O4.ClH/c1-2-16-4-3-5-17(12-16)25-22-18-13-20-21(14-19(18)23-15-24-22)29-11-9-27-7-6-26-8-10-28-20;/h1,3-5,12-15H,6-11H2,(H,23,24,25);1H |
InChI Key | PNNGXMJMUUJHAV-UHFFFAOYSA-N |
Antibiotic Activity Spectrum | neoplastics (Tumor) |
Solubility | Soluble in DMSO |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
