Irofulven
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Category | Antineoplastic |
Catalog number | BBF-05734 |
CAS | 158440-71-2 |
Molecular Weight | 246.12 |
Molecular Formula | C15H18O3 |
Purity | ≥95% |
Ordering Information
Catalog Number | Size | Price | Stock | Quantity |
---|---|---|---|---|
BBF-05734 | 5 mg | $1565 | In stock |
Online Inquiry
Add to cartDescription
Irofulven is a semisynthetic sesquiterpene derivative of illudin S, a natural toxin isolated from the fungus Omphalotus illudens. Irofulven alkylates DNA and protein macromolecules, forms adducts, and arrests cells in the S-phase of the cell cycle.
Specification
Synonyms | (6'R)-6'-Hydroxy-3'-(hydroxymethyl)-2',4',6'-trimethylspiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one; (-)-(Hydroxymethyl)acylfulvene; (-)-Irofulven; HMAF; MGI 114; NSC 683863; 6-Hydroxymethylacylfulvene; Hydroxymethylacylfulvene; (R)-6'-Hydroxy-3'-(hydroxymethyl)-2',4',6'-trimethylspiro(cyclopropane-1,5'-(5H)inden)-7'(6'H)-one |
Storage | Store at -20°C under inert atmosphere |
IUPAC Name | (5'R)-5'-hydroxy-1'-(hydroxymethyl)-2',5',7'-trimethylspiro[cyclopropane-1,6'-indene]-4'-one |
Canonical SMILES | CC1=C(C2=C(C3(CC3)C(C(=O)C2=C1)(C)O)C)CO |
InChI | InChI=1S/C15H18O3/c1-8-6-10-12(11(8)7-16)9(2)15(4-5-15)14(3,18)13(10)17/h6,16,18H,4-5,7H2,1-3H3/t14-/m0/s1 |
InChI Key | NICJCIQSJJKZAH-AWEZNQCLSA-N |
Properties
Appearance | Orange Solid |
Antibiotic Activity Spectrum | Neoplastics (Tumor) |
Boiling Point | 501.0±45.0°C at 760 mmHg |
Melting Point | 127-129°C |
Density | 1.3±0.1 g/cm3 |
Solubility | Soluble in Chloroform (Slightly), Ethyl Acetate (Slightly) |
Reference Reading
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2