Kanamycin A
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| Category | Antibiotics |
| Catalog number | BBF-01884 |
| CAS | 59-01-8 |
| Molecular Weight | 484.50 |
| Molecular Formula | C18H36N4O11 |
| Purity | 95% |
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Description
Kanamycin is an aminoglycoside antibiotic that has inhibitory effects on gram-positive and negative bacteria and mycoplasma. It can be used for the prevention and treatment of chicken pullorum, colibacillosis, enteritis and other diseases, and has a significant effect on systemic sepsis, respiratory tract infection, peritonitis, etc. caused by drug-resistant bacteria.
Specification
| Related CAS | 64013-70-3 (disulfate) 25389-94-0 (sulfate) |
| Synonyms | Amikacin EP Impurity D; O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine; 4,6-Diamino-2-hydroxy-1,3-cyclohexane 3,6'-diamino-3,6'-dideoxydi-α-D-glucoside; KM; Kanacin; Kanamycin; 6-O-(3-amino-3-deoxy-a-D-glucopyranosyl)-4-O-(6-amino-6-deoxy-a-D-glucopyranosyl)-2-deoxy-D-streptamine |
| Storage | Store at -20°C |
| IUPAC Name | (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol |
| Canonical SMILES | C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N |
| InChI | InChI=1S/C18H36N4O11/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17/h4-18,23-29H,1-3,19-22H2/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-/m1/s1 |
| InChI Key | SBUJHOSQTJFQJX-NOAMYHISSA-N |
Properties
| Appearance | White to Off-White Solid |
| Application | Anti-bacterial agents; protein synthesis inhibitors |
| Antibiotic Activity Spectrum | Gram-positive bacteria; Gram-negative bacteria; mycobacteria |
| Boiling Point | 809.5°C at 760 mmHg |
| Melting Point | >175°C (dec.) |
| Density | 1.62 g/cm3 |
| Solubility | Soluble in Methanol (Slightly, Sonicated), Water (Slightly) |
Reference Reading
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
