Karalicin

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Category Antibiotics
Catalog number BBF-01532
CAS
Molecular Weight 284.30
Molecular Formula C14H20O6

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Description

Karalicin is produced by the strain of Pseudomonus fluorescens/putida SS-3. It inhibits herpes simplex virus HSV-1, HSV-2, vaccinia virus, polio virus type I with the IC50 (μg/mL) of 0.004, 0.008, 0.016 and 0.016.

Specification

Synonyms 3-O-Acetyl-1-deoxy-1-(4-methoxyphenyl)pentitol
IUPAC Name [1,2,4-trihydroxy-5-(4-methoxyphenyl)pentan-3-yl] acetate
Canonical SMILES CC(=O)OC(C(CC1=CC=C(C=C1)OC)O)C(CO)O
InChI InChI=1S/C14H20O6/c1-9(16)20-14(13(18)8-15)12(17)7-10-3-5-11(19-2)6-4-10/h3-6,12-15,17-18H,7-8H2,1-2H3
InChI Key JATBUOZGJQJSGA-UHFFFAOYSA-N

Properties

Appearance Brown Powder
Antibiotic Activity Spectrum viruses
Melting Point 134-136°C

Reference Reading

1. Karalicin, a new biologically active compound from Pseudomonas fluorescens/putida. I. Production, isolation, physico-chemical properties and structure elucidation
G Lampis, D Deidda, C Maullu, S Petruzzelli, R Pompei, F D Monache, G Satta J Antibiot (Tokyo). 1996 Mar;49(3):260-2. doi: 10.7164/antibiotics.49.260.
An original compound, named karalicin, was isolated from a fermentation broth of the Pseudomonas fluorescens/putida strain SS-3 (CCM 4430). Production, physico-chemical properties and structure elucidation are described.
2. Karalicin, a new biologically active compound from Pseudomonas fluorescens/putida. II. Biological properties
G Lampis, D Deidda, C Maullu, S Petruzzelli, R Pompei, F D Monache, G Satta J Antibiot (Tokyo). 1996 Mar;49(3):263-6. doi: 10.7164/antibiotics.49.263.
The biological activities of karalicin, a new product from the Pseudomonas fluorescens/putida strain SS-3 (CCM 4430) are described. It shows a weak, but specific and irreversible, antiviral activity on Herpes simplex viruses. It also presents some inhibitory activity on different species of yeasts.

Bio Calculators

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
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