Kitamycin A
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Antibiotics |
| Catalog number | BBF-01550 |
| CAS | |
| Molecular Weight | 464.51 |
| Molecular Formula | C23H32N2O8 |
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Description
It is originally isolated from Strptomyces sp. K385. Kitamycin A can inhibit the activity of plant growth.
Specification
| IUPAC Name | 3-formamido-N-[(2R,3S,6S,7R,8R)-8-hexyl-7-hydroxy-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-3-yl]-2-hydroxybenzamide |
| Canonical SMILES | CCCCCCC1C(C(OC(=O)C(C(OC1=O)C)NC(=O)C2=C(C(=CC=C2)NC=O)O)C)O |
| InChI | InChI=1S/C23H32N2O8/c1-4-5-6-7-9-16-19(27)14(3)33-23(31)18(13(2)32-22(16)30)25-21(29)15-10-8-11-17(20(15)28)24-12-26/h8,10-14,16,18-19,27-28H,4-7,9H2,1-3H3,(H,24,26)(H,25,29)/t13-,14+,16-,18+,19+/m1/s1 |
| InChI Key | GTUQGSSCDLWNEE-KZYWPTACSA-N |
Properties
| Appearance | White Powder |
| Melting Point | 158-160°C |
Reference Reading
1. Kitamycin C, a new antimycin-type antibiotic from Streptomyces antibioticus strain 200-09
Fan Wang, Shu-Na Fu, Yi-Xuan Bao, Yu Yang, Hui-Fang Shen, Bi-Run Lin, Guang-Xiong Zhou Nat Prod Res. 2017 Aug;31(15):1819-1824. doi: 10.1080/14786419.2017.1295240. Epub 2017 Feb 28.
An actinomycete strain 200-09, isolated from a soil sample collected from the coast of Hawaii, USA, was identified as Streptomyces antibioticus on the basis of its morphological, physiological and biochemical characteristics as well as 16S rDNA analysis. A new antimycin-type antibiotic, kitamycin C (1), together with kitamycin A (2), kitamycin B (3), urauchmycin B (4), deisovaleryblastomycin (5) was isolated from a cultured broth of strain 200-09. The structure of the new compound was determined by spectroscopic data, including HR-ESI-MS and NMR. All the compounds exhibited antifungal activities against Candida albicans with MIC of about 25.0 μg mL-1.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
