L-156602

L-156602

Catalog number:

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It is produced by the strain of Nocardia sp. C-15003(N-1). It has the function of anti-tumor, anti-plant pathogenic fungi, skin fungi and protozoa, and has no antibacterial activity.

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Catalog Number BBF-03707
CAS 125228-51-5
Description L-156602 is extracted from Streptomyces sp. MA6348, and it is the antagonist of Anaphylatoxin C5a. It is also a cyclic depsipeptide antibiotic that is active against Gram-positive bacteria.
Molecular Formula C38H64N8O13
Molecular Weight 840.96
Antibiotic Activity Spectrum Gram-positive bacteria
Synonyms Antibiotic L 156602; Antibiotic PD-124966; GNF-Pf-75; L 156602; PD-124966; (3S)-3-hydroxy-N-[(2S)-2-hydroxy-1-oxo-2-[(2R,5R,6R)-tetrahydro-2-hydroxy-6-methyl-5-[(2S)-2-methylbutyl]-2H-pyran-2-yl]propyl]-L-leucyl-(3R)-hexahydro-3-pyridazinecarbonyl-N-hydroxy-L-alanylglycyl-(3S)-hexahydro-3-pyridazinecarbonyl-N-hydroxy-D-alanine, (6→13)-lactone
IUPAC Name (2S)-N-[(6S,9S,16S,17S,20R,23R)-7,21-dihydroxy-6,20-dimethyl-2,5,8,15,19,22-hexaoxo-17-propan-2-yl-18-oxa-1,4,7,13,14,21,27-heptazatricyclo[21.4.0.09,14]heptacosan-16-yl]-2-hydroxy-2-[(2R,5R,6R)-2-hydroxy-6-methyl-5-[(2S)-2-methylbutyl]oxan-2-yl]propanamide
Canonical SMILES CCC(C)CC1CCC(OC1C)(C(C)(C(=O)NC2C(OC(=O)C(N(C(=O)C3CCCNN3C(=O)CNC(=O)C(N(C(=O)C4CCCNN4C2=O)O)C)O)C)C(C)C)O)O
InChI InChI=1S/C38H64N8O13/c1-9-21(4)18-25-14-15-38(55,59-24(25)7)37(8,54)36(53)42-29-30(20(2)3)58-35(52)23(6)46(57)32(49)26-12-10-16-40-43(26)28(47)19-39-31(48)22(5)45(56)33(50)27-13-11-17-41-44(27)34(29)51/h20-27,29-30,40-41,54-57H,9-19H2,1-8H3,(H,39,48)(H,42,53)/t21-,22-,23+,24+,25+,26+,27-,29-,30-,37+,38+/m0/s1
InChI Key ZJZOPNINWIGNQW-INBMEMTISA-N
Melting Point 190-193°C
Purity >95% by HPLC
Density 1.4±0.1 g/cm3
Solubility Soluble in Ethanol, Methanol, DMF, DMSO
Appearance Colorless Acicular Crystal
Storage Store at -20°C

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