L-Lysinol

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L-Lysinol
Category Others
Catalog number BBF-04750
CAS 110690-36-3
Molecular Weight 132.21
Molecular Formula C6H16N2O

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Specification

Synonyms H-Lys-ol; (S)-2,6-Diaminohexan-1-ol; (2S)-2,6-Diaminohexan-1-ol
Storage Store at 2-8 °C
IUPAC Name (2S)-2,6-diaminohexan-1-ol
Canonical SMILES C(CCN)CC(CO)N
InChI InChI=1S/C6H16N2O/c7-4-2-1-3-6(8)5-9/h6,9H,1-5,7-8H2/t6-/m0/s1
InChI Key LTGPFZWZZNUIIK-LURJTMIESA-N

Reference Reading

1. Synthesis of protected 3-aminopiperidine and 3-aminoazepane derivatives using enzyme cascades
Grayson J Ford, Nico Kress, Ashley P Mattey, Lorna J Hepworth, Christopher R Baldwin, James R Marshall, Lisa S Seibt, Min Huang, William R Birmingham, Nicholas J Turner, Sabine L Flitsch Chem Commun (Camb). 2020 Jul 21;56(57):7949-7952. doi: 10.1039/d0cc02976a. Epub 2020 Jun 12.
Multi-enzyme cascades utilising variants of galactose oxidase and imine reductase led to the successful conversion of N-Cbz-protected l-ornithinol and l-lysinol to l-3-N-Cbz-aminopiperidine and l-3-N-Cbz-aminoazepane respectively, in up to 54% isolated yield. Streamlining the reactions into one-pot prevented potential racemisation of key labile intermediates and led to products with high enantiopurity.

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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