LL-AB 664
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Antibiotics |
| Catalog number | BBF-03617 |
| CAS | 29266-98-6 |
| Molecular Weight | 486.49 |
| Molecular Formula | C18H30N8O8 |
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Description
LL-AB 664 is originally isolated from Streptomyces candidus. It has a wide antibacterial spectrum and can protect mice from infections caused by Escherichia coli, Klebsiella pneumoniae, Typhoid and Staphylococcus aureus when given subcutaneously.
Specification
| Synonyms | Antibiotic LL-AB 664; BD 12; 4H-Imidazo(4,5-c)pyridin-4-one, 1,3a,5,6,7,7a-hexahydro-2-((2-deoxy-2-(2-(formimidoylamino)-N-methylacetamido)-beta-D-gulopyranosyl)amino)-7-hydroxy-5-methyl-, 3'-carbamate |
| IUPAC Name | [(2R,3R,4S,5R,6R)-6-[[(3aS,7R,7aS)-7-hydroxy-5-methyl-4-oxo-3a,6,7,7a-tetrahydro-1H-imidazo[4,5-c]pyridin-2-yl]amino]-5-[[2-(aminomethylideneamino)acetyl]-methylamino]-4-hydroxy-2-(hydroxymethyl)oxan-3-yl] carbamate |
| Canonical SMILES | CN1CC(C2C(C1=O)N=C(N2)NC3C(C(C(C(O3)CO)OC(=O)N)O)N(C)C(=O)CN=CN)O |
| InChI | InChI=1S/C18H30N8O8/c1-25-4-7(28)10-11(16(25)31)23-18(22-10)24-15-12(26(2)9(29)3-21-6-19)13(30)14(34-17(20)32)8(5-27)33-15/h6-8,10-15,27-28,30H,3-5H2,1-2H3,(H2,19,21)(H2,20,32)(H2,22,23,24)/t7-,8-,10-,11+,12-,13+,14+,15-/m1/s1 |
| InChI Key | VMULEITVZASJMA-BBLFBTFMSA-N |
Properties
| Antibiotic Activity Spectrum | Gram-positive bacteria; Gram-negative bacteria |
| Boiling Point | 876.4°C at 760 mmHg |
| Density | 1.83 g/cm3 |
Reference Reading
1. Presepsin: Hope in the Quest for the Holy Grail
Abhishek Samprathi, Madhusudan Samprathi, Mounika Reddy Indian J Crit Care Med. 2022 Jun;26(6):664-666. doi: 10.5005/jp-journals-10071-24251.
How to cite this article: Samprathi A, Samprathi M, Reddy M. Presepsin: Hope in the Quest for the Holy Grail. Indian J Crit Care Med 2022;26(6):664-666.
2. [Retracted] MicroRNA‑664 targets paired box protein 6 to inhibit the oncogenicity of pancreatic ductal adenocarcinoma
Qi Wang, Jiaqi Wang, Songtao Niu, Songsong Wang, Yibin Liu, Xiaoya Wang Int J Oncol. 2022 Aug;61(2):90. doi: 10.3892/ijo.2022.5380. Epub 2022 Jun 8.
Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that several of the panels showing flow cytometric assay data in Figs. 2D, 5D and 6E, western blotting data featured in Fig. 7, and certain of the cell migration assay data panels included in Fig. 5E and F and Fig. 6G were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to International Journal of Oncology, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused. [International Journal of Oncology 54: 1884‑1896, 2019; DOI: 10.3892/ijo.2019.4759].
3. Communal collective narcissism
Magdalena Żemojtel-Piotrowska, Jarosław Piotrowski, Constantine Sedikides, Artur Sawicki, Anna Z Czarna, Ramzi Fatfouta, Tomasz Baran J Pers. 2021 Oct;89(5):1062-1080. doi: 10.1111/jopy.12636. Epub 2021 Apr 24.
Objectives: We aimed to introduce, validate, and showcase the utility of a new construct: communal collective narcissism. Method: We conducted four studies, in which we developed a new scale for communal collective narcissism (Study 1, N = 856), tested the construct's unique predictions (Study 2, N = 276), examined its social relevance (Study 3, N = 250), and assessed its implications for intergroup outcomes (Study 4, N = 664). Results: In Study 1, we verified the structural soundness of the Communal Collective Narcissism Inventory. In Study 2, we obtained evidence for a defining feature of communal collective narcissism, namely, that it predicts communal, but not agentic, ingroup-enhancement. In Study 3, we illustrated the social relevance of communal collective narcissism. Communal collective narcissists derogated outgroup members, if those outgroups threatened the ingroup and the threat targeted the ingroup's communion. Finally, in Study 4, we showed that communal collective narcissism predicts intergroup outcomes in the communal domain (e.g., humanitarian aid) better than agentic collective narcissism does, whereas agentic collective narcissism predicts intergroup outcomes in the agentic domain (i.e., preferences for military aggression) better than communal collective narcissism does. Conclusions: The construct of communal collective narcissism is conceptually and empirically distinct from classic (i.e., agentic) collective narcissism.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
