LL-F 28249lambda
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| Category | Antibiotics |
| Catalog number | BBF-03629 |
| CAS | 102042-12-6 |
| Molecular Weight | 626.82 |
| Molecular Formula | C37H54O8 |
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Description
LL-F 28249lambda is a macrolide antibiotic with parasitic action from Streptomyces Cyaneogriseus sp. Noncyanogenus.
Specification
| Synonyms | LL-F28249 Lambda; Milbemycin B, 28-deoxy-25-(1,3-dimethyl-1-butenyl)-6,28-epoxy-23-hydroxy- |
| IUPAC Name | (4S,4'S,5'S,6'S,8R,10E,13R,14E,16E,20R,21R,24S)-4',24-dihydroxy-21-methoxy-5',11,13,22-tetramethyl-6'-[(E)-4-methylpent-2-en-2-yl]spiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one |
| Canonical SMILES | CC1CC(=CCC2CC(CC3(O2)CC(C(C(O3)C(=CC(C)C)C)C)O)OC(=O)C4C=C(C(C5C4(C(=CC=C1)CO5)O)OC)C)C |
| InChI | InChI=1S/C37H54O8/c1-21(2)14-24(5)32-26(7)31(38)19-36(45-32)18-29-17-28(44-36)13-12-23(4)15-22(3)10-9-11-27-20-42-34-33(41-8)25(6)16-30(35(39)43-29)37(27,34)40/h9-12,14,16,21-22,26,28-34,38,40H,13,15,17-20H2,1-8H3/b10-9+,23-12+,24-14+,27-11+/t22-,26-,28+,29-,30?,31-,32+,33+,34+,36?,37+/m0/s1 |
| InChI Key | VEMTVKZJFSDFNW-ZFUGZJOKSA-N |
Properties
| Antibiotic Activity Spectrum | parasites |
| Boiling Point | 772.5°C at 760 mmHg |
| Density | 1.17 g/cm3 |
Reference Reading
1. LL-F28249 antibiotic complex: a new family of antiparasitic macrocyclic lactones. Isolation, characterization and structures of LL-F28249 alpha, beta, gamma, lambda
G T Carter, J A Nietsche, M R Hertz, D R Williams, M M Siegel, G O Morton, J C James, D B Borders J Antibiot (Tokyo). 1988 Apr;41(4):519-29. doi: 10.7164/antibiotics.41.519.
A new family of antiparasitic macrolides has been isolated from Streptomyces cyaneogriseus sp. noncyanogenus. The compounds, designated LL-F28249 alpha, beta, gamma and lambda, possess potent antiparasitic activity. The isolation, purification and structure determination by spectroscopic methods are presented.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
