Lysyl-glutamine
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| Category | Others |
| Catalog number | BBF-05656 |
| CAS | 92352-82-4 |
| Molecular Weight | 274.32 |
| Molecular Formula | C11H22N4O4 |
| Purity | ≥95% |
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Description
Lysyl-glutamine is a dipeptide composed of Lysine and glutamine. It is an incomplete breakdown product of protein digestion or protein catabolism.
Specification
| Synonyms | L-Glutamine, N2-L-lysyl-; L-Lysyl-L-glutamine; Lys-Gln; Lysylglutamine; H-KQ-OH; N-(2,6-Diamino-1-hydroxyhexylidene)-5-hydroxy-5-iminonorvaline; L-Lys-L-Gln |
| Sequence | H-Lys-Gln-OH |
| IUPAC Name | (2S)-5-amino-2-[[(2S)-2,6-diaminohexanoyl]amino]-5-oxopentanoic acid |
| Canonical SMILES | C(CCN)CC(C(=O)NC(CCC(=O)N)C(=O)O)N |
| InChI | InChI=1S/C11H22N4O4/c12-6-2-1-3-7(13)10(17)15-8(11(18)19)4-5-9(14)16/h7-8H,1-6,12-13H2,(H2,14,16)(H,15,17)(H,18,19)/t7-,8-/m0/s1 |
| InChI Key | OAPNERBWQWUPTI-YUMQZZPRSA-N |
Properties
| Appearance | Solid |
| Boiling Point | 673.9±55.0°C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Solubility | Soluble in Water |
Reference Reading
1. Purification of a synthetic myristylated peptide by counter-current chromatography
M Knight, S Gluch, K Takahashi, T T Dang, R A Kahn J Chromatogr. 1991 Jan 18;538(1):141-7. doi: 10.1016/s0021-9673(01)91631-0.
A preparative purification of myristyl-Gly-Asn-Ile-Phe-Ala-Asn-Leu-Phe-Lys-Gly-Leu-Phe-Gly-Lys-Lys-Glu -NH2 was accomplished using the multi-coil counter-current chromatograph. A partition coefficient was determined in the n-butanol-acetic acid-water (4:1:5) system. Chromatographic runs were made in this system and one modified with ethyl acetate. The peptide material showed anomalous elution behavior due to its surfactant properties. It was found that by loading the sample exclusively in the stationary phase, satisfactory retention of the compound occurred. Finally, conditions utilizing the upper phase as the mobile phase successfully separated the impurities.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
