L-Lysyl-L-glutamine

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L-Lysyl-L-glutamine
Category Others
Catalog number BBF-05656
CAS 92352-82-4
Molecular Weight 274.32
Molecular Formula C11H22N4O4
Purity ≥95%

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Description

L-Lysyl-L-glutamine is a dipeptide made up of L-lysine and L-glutamine. L-lysine is an essential amino acid important for protein synthesis, tissue repair, and the production of enzymes and hormones, while L-glutamine supports immune function, nitrogen transport, and intestinal health. This dipeptide could be of interest in studies exploring amino acid supplementation, protein metabolism, or immune system support, as well as in potential therapeutic applications targeting muscle recovery or gut health.

Specification

Related CAS 92352-83-5 (homopolymer)
Synonyms KQ; Lysyl-glutamine; H-Lys-Gln-OH; H-KQ-OH; Lys-Gln; L-Glutamine, N2-L-lysyl-; Lysylglutamine; KQ dipeptide; K-Q Dipeptide; L-Lys-L-Gln; Lysine Glutamine dipeptide
Sequence Lys-Gln
IUPAC Name (2S)-5-amino-2-[[(2S)-2,6-diaminohexanoyl]amino]-5-oxopentanoic acid
Canonical SMILES C(CCN)CC(C(=O)NC(CCC(=O)N)C(=O)O)N
InChI InChI=1S/C11H22N4O4/c12-6-2-1-3-7(13)10(17)15-8(11(18)19)4-5-9(14)16/h7-8H,1-6,12-13H2,(H2,14,16)(H,15,17)(H,18,19)/t7-,8-/m0/s1
InChI Key OAPNERBWQWUPTI-YUMQZZPRSA-N

Properties

Appearance Solid
Boiling Point 673.9±55.0 °C at 760 mmHg
Density 1.249±0.06 g/cm3
Solubility Soluble in Water

Reference Reading

1. Purification of a synthetic myristylated peptide by counter-current chromatography
M Knight, S Gluch, K Takahashi, T T Dang, R A Kahn J Chromatogr. 1991 Jan 18;538(1):141-7. doi: 10.1016/s0021-9673(01)91631-0.
A preparative purification of myristyl-Gly-Asn-Ile-Phe-Ala-Asn-Leu-Phe-Lys-Gly-Leu-Phe-Gly-Lys-Lys-Glu -NH2 was accomplished using the multi-coil counter-current chromatograph. A partition coefficient was determined in the n-butanol-acetic acid-water (4:1:5) system. Chromatographic runs were made in this system and one modified with ethyl acetate. The peptide material showed anomalous elution behavior due to its surfactant properties. It was found that by loading the sample exclusively in the stationary phase, satisfactory retention of the compound occurred. Finally, conditions utilizing the upper phase as the mobile phase successfully separated the impurities.

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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