Martinomycin
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| Category | Antibiotics |
| Catalog number | BBF-02661 |
| CAS | 160791-16-2 |
| Molecular Weight | 945.18 |
| Molecular Formula | C49H84O17 |
| Purity | ≥95% |
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Description
It is produced by the strain of Str. salvialis. It's a polyether antibiotic. It has strong anti-gram-positive bacteria activity, but no anti-gram-negative bacteria activity. It also acts as a pesticide.
Specification
| Synonyms | 2H-Pyran-2-acetic acid, 6-[[(2R,3R,4R,5S,7S,9R,10R)-3,9-dimethoxy-2,4,10-trimethyl-2-[(2S,2'R,5R,5'R)-octahydro-5'-[(2S,3S,4S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-4-[[(2R,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl]oxy]-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-1,6-dioxaspiro[4.5]dec-7-yl]methyl]tetrahydro-2-hydroxy-4,5-dimethoxy-a,3,5-trimethyl-, (aR,2S,3S,4S,5S,6S)-; AntibioticK 41, 2-deoxy-2-methyl-; 2H-Pyran-2-acetic acid, 6-[[3,9-dimethoxy-2,4,10-trimethyl-2-[octahydro-5'-[tetrahydro-6-hydroxy-3,5,6-trimethyl-4-[(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy]-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-1,6-dioxaspiro[4.5]dec-7-yl]methyl]tetrahydro-2-hydroxy-4,5-dimethoxy-a,3,5-trimethyl-, [2S-[2a,2(S*),3a,4b,5a,6b[2S*[2R*,2'S*,5S*,5'S*[2R*,3R*,4R*(2S*,5R*,6S*),5S*,6R*]],3S*,4S*,5R*,7R*,9S*,10S*]]]- |
| IUPAC Name | (2R)-2-[(2S,3S,4S,5S,6S)-2-hydroxy-6-[[(2R,3R,4R,5S,6R,7R,9S)-2-[(2R,5S)-5-[(2R,5R)-5-[(2S,3S,4S,5R,6S)-6-hydroxy-4-[(2R,5S,6R)-5-methoxy-6-methyloxan-2-yl]oxy-3,5,6-trimethyloxan-2-yl]oxolan-2-yl]oxolan-2-yl]-3,7-dimethoxy-2,4,6-trimethyl-1,10-dioxaspiro[4.5]decan-9-yl]methyl]-4,5-dimethoxy-3,5-dimethyloxan-2-yl]propanoic acid |
| Canonical SMILES | CC1C(OC(C(C1OC2CCC(C(O2)C)OC)C)(C)O)C3CCC(O3)C4CCC(O4)C5(C(C(C6(O5)C(C(CC(O6)CC7C(C(C(C(O7)(C(C)C(=O)O)O)C)OC)(C)OC)OC)C)C)OC)C |
| InChI | InChI=1S/C49H84O17/c1-24-40(62-39-21-19-32(54-11)30(7)59-39)26(3)47(10,52)65-41(24)35-17-16-33(60-35)34-18-20-37(61-34)46(9)43(57-14)28(5)49(66-46)25(2)36(55-12)22-31(63-49)23-38-45(8,58-15)42(56-13)27(4)48(53,64-38)29(6)44(50)51/h24-43,52-53H,16-23H2,1-15H3,(H,50,51)/t24-,25+,26+,27-,28+,29-,30+,31-,32-,33+,34-,35+,36+,37+,38-,39-,40-,41-,42-,43+,45-,46+,47-,48-,49-/m0/s1 |
| InChI Key | VIAPPZHHJMCDEJ-JXBMCXTESA-N |
Properties
| Appearance | Villous White Solid |
| Antibiotic Activity Spectrum | Gram-positive bacteria |
| Solubility | Soluble in Chloroform |
Reference Reading
1. Martinomycin, a new polyether antibiotic produced by Streptomyces salvialis. I. Taxonomy, fermentation and biological activity
J J Goodman, W M Maiese, M Greenstein, M R Alluri, D R Abbanat, G T Carter, D A Montenegro, V S Bernan, C J Pearce J Antibiot (Tokyo) . 1994 Dec;47(12):1434-41. doi: 10.7164/antibiotics.47.1434.
Actinomycete culture LL-D37187 has been found to produce the new polyether antibiotic martinomycin. Taxonomic studies, including morphological, physiological, and cell wall chemistry analyses, revealed that culture LL-D37187 is a novel streptomycete species, and the proposed name is Streptomyces salvialis. Martinomycin exhibits activity against the Southern Army Worm (Spodoptera eridania) and Gram-positive bacteria.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
