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Memnobotrin A

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Memnobotrin A
Category Antibiotics
Catalog number BBF-01917
CAS
Molecular Weight 427.53
Molecular Formula C25H33NO5

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Capabilities & Facilities

Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

Memnobotrin A is an antibiotic produced by Memnoniella echinata (JS6308). It has inhibitory effect on NCI-460, MCF7 and SF-268 cell lines.

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IUPAC Name [(1S,13R,14S,17S,19R)-10-hydroxy-1,14,18,18-tetramethyl-7-oxo-2-oxa-6-azapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3,8,10-trien-17-yl] acetate
Canonical SMILES CC(=O)OC1CCC2(C(C1(C)C)CCC3(C2CC4=C(C=C5C(=C4O3)CNC5=O)O)C)C
InChI InChI=1S/C25H33NO5/c1-13(27)30-20-7-8-24(4)18(23(20,2)3)6-9-25(5)19(24)11-15-17(28)10-14-16(21(15)31-25)12-26-22(14)29/h10,18-20,28H,6-9,11-12H2,1-5H3,(H,26,29)/t18-,19+,20-,24-,25-/m0/s1
InChI Key ICUVEGRXTWNIKO-BOWIAGTOSA-N
Appearance Light Yellow Crystal
Boiling Point 617.9±55.0°C at 760 mmHg
Melting Point 240-245°C (dec.)
Density 1.3±0.1 g/cm3
1. Memnobotrins and memnoconols: novel metabolites from Memnoniella echinata
S F Hinkley, J C Fettinger, K Dudley, B B Jarvis J Antibiot (Tokyo). 1999 Nov;52(11):988-97. doi: 10.7164/antibiotics.52.988.
Four novel metabolites have been isolated from a rice culture of Memnoniella echinata (JS6308) by solvent extraction and radial silica chromatography. The structures were elucidated by spectroscopic techniques, and the absolute stereochemistry of memnobotrin A determined by X-ray crystallography.

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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