Menoxymycin A

Menoxymycin A

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Category Antibiotics
Catalog number BBF-01922
CAS 160492-65-9
Molecular Weight 473.47
Molecular Formula C24H27NO9

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Description

Menoxymycin A is an antibiotic produced by Str. sp. KB10. It has a cytotoxic effect. It inhibits KB and N18-RE-105 cells with IC50 of 0.86 μmol/L and 0.14 μmol/L. Dithiothreitol (DDT) can reduce A and B cytotoxicity effect.

Specification

Synonyms [(2R)-2alpha-Methyl-3beta-hydroxy-6alpha-[(3aR)-2,6,11-trioxo-5alpha-methyl-7-hydroxy-3,3aalpha,5,6,11,11balpha-hexahydro-2H-furo[3,2-b]naphtho[2,3-d]pyran-10-yl]tetrahydro-2H-pyran-4alpha-yl]dimethylamine oxide
IUPAC Name (2R,3S,4R,6R)-3-hydroxy-6-[(11R,15R,17R)-4-hydroxy-17-methyl-2,9,13-trioxo-12,16-dioxatetracyclo[8.7.0.03,8.011,15]heptadeca-1(10),3,5,7-tetraen-7-yl]-N,N,2-trimethyloxan-4-amine oxide
Canonical SMILES CC1C(C(CC(O1)C2=C3C(=C(C=C2)O)C(=O)C4=C(C3=O)C5C(CC(=O)O5)OC4C)[N+](C)(C)[O-])O
InChI InChI=1S/C24H27NO9/c1-9-17-20(24-15(32-9)8-16(27)34-24)23(30)18-11(5-6-13(26)19(18)22(17)29)14-7-12(25(3,4)31)21(28)10(2)33-14/h5-6,9-10,12,14-15,21,24,26,28H,7-8H2,1-4H3/t9-,10-,12-,14-,15-,21-,24+/m1/s1
InChI Key AFVFOGCWMMKRCH-HNWASVEASA-N

Properties

Appearance Yellow Powder
Boiling Point 718.4±60.0°C at 760 mmHg
Melting Point 168-173°C (dec.)
Density 1.4±0.1 g/cm3

Bio Calculators

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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