Mevastatin
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| Category | Enzyme inhibitors |
| Catalog number | BBF-01732 |
| CAS | 73573-88-3 |
| Molecular Weight | 390.51 |
| Molecular Formula | C23H34O5 |
| Purity | >98% |
Ordering Information
| Catalog Number | Size | Price | Stock | Quantity |
|---|---|---|---|---|
| BBF-01732 | 25 g | $298 | In stock |
Online Inquiry
Add to cartDescription
It is produced by the strain of Penicillum brevicompactum. It has weak anti-fungal activity and can inhibit the key enzyme (3-hydroxy-3-methyl glutaryl coenzyme A(HMGCoA) reductase) in the cholesterol biosynthesis pathway. It has been shown to lower cholesterol in animals and humans. It led the discovery of statins, lipid-lowering drugs. It is now used as a biochemical reagent.
Specification
| Synonyms | Mevastatina; Mevastatine; Mevastatinum; ML-236B; Compactin; CS-500; CS 500; CS500; ML-236B; ML 236B; ML236B; Antibiotic ML 236B |
| Storage | -20 °C |
| IUPAC Name | [(1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate |
| Canonical SMILES | CCC(C)C(=O)OC1CCC=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O |
| InChI | InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1 |
| InChI Key | AJLFOPYRIVGYMJ-INTXDZFKSA-N |
| Source | Penicillium sp. |
Properties
| Appearance | White to Off-White Solid |
| Application | Hydroxymethylglutaryl-CoA Reductase Inhibitors |
| Antibiotic Activity Spectrum | Fungi |
| Boiling Point | 555.0±50.0 °C (Predicted) |
| Melting Point | > 135 °C (dec.) |
| Density | 1.13±0.1 g/cm3 (Predicted) |
| Solubility | Soluble in Methanol, Acetone, Ethanol, DMF, DMSO |
Reference Reading
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
