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Micacocidin C

Name: Micacocidin C
Brand: BOC Sciences
Rating: 5 (1 reviews)

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category	Antibiotics
Catalog number	BBF-01935
CAS
Molecular Weight	618.63
Molecular Formula	C27H36FeN3O4S3

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Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

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Micacocidin C is an antibiotic produced by Pseudomonas sp.No.57. It exhibited an excellent activity against Mycoplasma species.

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IUPAC Name	iron(3+);(4S)-4-methyl-2-[(1R)-2-methyl-1-[(2R,4R)-3-methyl-2-[(4R)-2-(2-oxido-6-pentylphenyl)-4,5-dihydro-1,3-thiazol-4-yl]-1,3-thiazolidin-4-yl]-1-oxidopropan-2-yl]-5H-1,3-thiazole-4-carboxylate
Canonical SMILES	CCCCCC1=C(C(=CC=C1)[O-])C2=NC(CS2)C3N(C(CS3)C(C(C)(C)C4=NC(CS4)(C)C(=O)[O-])[O-])C.[Fe+3]
InChI	InChI=1S/C27H38N3O4S3.Fe/c1-6-7-8-10-16-11-9-12-19(31)20(16)22-28-17(13-35-22)23-30(5)18(14-36-23)21(32)26(2,3)24-29-27(4,15-37-24)25(33)34;/h9,11-12,17-18,21,23,31H,6-8,10,13-15H2,1-5H3,(H,33,34);/q-1;+3/p-2/t17-,18+,21+,23-,27-;/m1./s1
InChI Key	ANYHWHQDULLETA-LRLOAOIRSA-L

Appearance	Reddish Brown Powder
Antibiotic Activity Spectrum	mycoplasma
Boiling Point	740.3±70.0°C at 760 mmHg
Density	1.4±0.1 g/cm3

1. Micacocidin A, B and C, novel antimycoplasma agents from Pseudomonas sp. II. Structure elucidation

S Kobayashi, H Nakai, Y Ikenishi, W Y Sun, M Ozaki, Y Hayase, R Takeda J Antibiot (Tokyo). 1998 Mar;51(3):328-32. doi: 10.7164/antibiotics.51.328.

Metal-containing novel heterocyclic antibiotics, micacocidin A (1), B (2), and C (3) have been isolated from the culture filtrate of Pseudomonas sp. No. 57-250. The structure and absolute configuration of micacocidin A, an octahedral Zn2+ complex, was determined by X-ray crystallographic analysis. And then, the structures of the two congeners, micacocidin B (Cu2+ complex) and C (Fe3+ complex) were investigated by employing one dimensional and two dimensional homonuclear and heteronuclear NMR spectroscopies and mass spectrometry.

2. Micacocidin A, B and C, novel antimycoplasma agents from Pseudomonas sp. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities

S Kobayashi, S Hidaka, Y Kawamura, M Ozaki, Y Hayase J Antibiot (Tokyo). 1998 Mar;51(3):323-7. doi: 10.7164/antibiotics.51.323.

A Gram-negative bacterium was found to produce a new zinc-containing antibiotics, micacocidin A and related compounds containing Cu or Fe, micacocidin B and C, respectively. These antibiotics were isolated by column chromatography on silica gel, and then separated by preparative TLC and HPLC. These new antibiotics exhibited an excellent activity against Mycoplasma species. The producing bacterium was characterized and ascribed to the genus Pseudomonas.

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