Mithramycin A
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category | Antibiotics |
Catalog number | BBF-02556 |
CAS | 18378-89-7 |
Molecular Weight | 1085.14 |
Molecular Formula | C52H76O24 |
Purity | ≥95% by HPLC |
Catalog Number | Size | Price | Stock | Quantity |
---|---|---|---|---|
BBF-02556 | 10 mg | $299 | In stock |
Online Inquiry
Add to cartCapabilities & Facilities
Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
Mithramycin A is an antineoplastic antibiotic produced by Streptomyces plicatus. Mithramycin A is a polymerase inhibitor that binds to GC rich sequences located in the minor groove of DNA.
- Specification
- Properties
- Reference Reading
- Price Product List
Synonyms | D-threo-2-Pentulose, 5-deoxy-1-C-[(2S,3S)-7-[[2,6-dideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-β-D-ribo-hexopyranosyl-(1→3)-O-2,6-dideoxy-β-D-lyxo-hexopyranosyl-(1→3)-2,6-dideoxy-β-D-arabino-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-, (1S)-; [1S(2S,3S)]-5-Deoxy-1-C-[7-[[2,6-dideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-β-D-ribo-hexopyranosyl-(1→3)-O-2,6-dideoxy-β-D-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-β-D-lyxo-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-D-threo-2-pentulose; A 2371; Antibiotic LA 7017; Aureolic acid; Mithracin; Mithramycin A; Mitramycin; NSC 24559; PA 144; Plicamycin; Plicatomycin |
Shelf Life | Hygroscopic, Decomp Slowly In Light, & Decomp In Heat |
Storage | Store at -20 °C, sealed storage, away from light |
IUPAC Name | (2S,3S)-2-[(2S,4R,5R,6R)-4-[(2S,4R,5S,6R)-4-[(2S,4S,5R,6R)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-3-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-6-[(2S,4R,5R,6R)-4-[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-8,9-dihydroxy-7-methyl-3,4-dihydro-2H-anthracen-1-one |
Canonical SMILES | O=C1C2=C(O)C3=C(O)C(=C(OC4OC(C)C(O)C(OC5OC(C)C(O)C(O)C5)C4)C=C3C=C2CC(C1OC6OC(C)C(O)C(OC7OC(C)C(O)C(OC8OC(C)C(O)C(O)(C)C8)C7)C6)C(OC)C(=O)C(O)C(O)C)C |
InChI | InChI=1S/C52H76O24/c1-18-29(72-34-14-30(43(58)21(4)68-34)73-33-13-28(54)42(57)20(3)67-33)12-26-10-25-11-27(49(66-9)48(63)41(56)19(2)53)50(47(62)39(25)46(61)38(26)40(18)55)76-36-16-31(44(59)23(6)70-36)74-35-15-32(45(60)22(5)69-35)75-37-17-52(8,65)51(64)24(7)71-37/h10,12,19-24,27-28,30-37,41-45,49-51,53-61,64-65H,11,13-17H2,1-9H3/t19-,20-,21-,22-,23-,24-,27+,28-,30-,31-,32-,33+,34+,35+,36+,37+,41+,42-,43-,44-,45+,49+,50+,51-,52+/m1/s1 |
InChI Key | CFCUWKMKBJTWLW-BKHRDMLASA-N |
Source | Streptomyces argillaceus |
Appearance | Yellow powder |
Application | antibiotics, Antineoplastic, Fluorescent dyes, Nucleic acid synthesis inhibitors, Protein synthesis inhibitors |
Antibiotic Activity Spectrum | Gram-positive bacteria; mycobacteria |
Boiling Point | 1169.8±65.0 °C at 760 mmHg |
Melting Point | 180-183 °C |
Density | 1.48±0.1 g/cm3 |
Solubility | Soluble in DMF, DMSO, Ethanol, Methanol, Water (Poorly) |
LogP | -0.25 at pH 7.4 |
BBF-03428 | Tubermycin B | Inquiry |
BBF-03211 | AT-265 | Inquiry |
BBF-00852 | Epothilon B | Inquiry |
BBF-00968 | Homoalanosine | Inquiry |
BBF-03427 | Tubercidin | Inquiry |
BBF-04727 | Strigolactone GR24 | Inquiry |
Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
