MM 14201

MM 14201

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Category Antibiotics
Catalog number BBF-03663
CAS 89020-30-4
Molecular Weight 141.12
Molecular Formula C6H7NO3

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Description

It is produced by the strain of Streptomyces sp. NCIB 11813. MM 14201 has a broad spectrum of antibacterial activity, especially against the bacteria of Serratia and Pseudomonas.

Specification

Synonyms MM-14201; 7-Oxabicyclo(4.1.0)hept-3-en-2-one, 3-amino-5-hydroxy-, (1S-(1alpha,5beta,6alpha))-
IUPAC Name (1S,5S,6S)-3-amino-5-hydroxy-7-oxabicyclo[4.1.0]hept-3-en-2-one
Canonical SMILES C1=C(C(=O)C2C(C1O)O2)N
InChI InChI=1S/C6H7NO3/c7-2-1-3(8)5-6(10-5)4(2)9/h1,3,5-6,8H,7H2/t3-,5-,6+/m0/s1
InChI Key OIXFFAVTKPAUAU-ZXEDONINSA-N

Properties

Antibiotic Activity Spectrum Gram-negative bacteria
Boiling Point 431°C at 760 mmHg
Density 1.592 g/cm3

Reference Reading

1. MM 14201, a new epoxyquinone derivative with antibacterial activity produced by a species of Streptomyces
S J Box, M L Gilpin, M Gwynn, G Hanscomb, S R Spear, A G Brown J Antibiot (Tokyo). 1983 Dec;36(12):1631-7. doi: 10.7164/antibiotics.36.1631.
A new antibiotic designated MM 14201 has been detected in a culture of Streptomyces sp. NCIB 11813. Methods for the production and purification of MM 14201 are described. Biological evaluation has shown it has broad spectrum antibacterial activity being most effective against Serratia and Pseudomonas sp. Structural studies are reported which have demonstrated MM 14201 is a new epoxyquinone derivative.

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