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MM 42842

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Category Antibiotics
Catalog number BBF-03665
CAS 113784-28-4
Molecular Weight 410.40
Molecular Formula C13H22N4O9S
Purity >98%

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Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

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Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

MM 42842 is originally isolated from Pseudomonas cocovenenans and has weak activity against gram-positive bacteria.

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Synonyms MM-42842
IUPAC Name (2S)-2-amino-5-[[1-[[(2R,3R)-3-methoxy-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
Canonical SMILES CC1C(C(=O)N1S(=O)(=O)O)(NC(=O)C(C)NC(=O)CCC(C(=O)O)N)OC
InChI InChI=1S/C13H22N4O9S/c1-6(15-9(18)5-4-8(14)11(20)21)10(19)16-13(26-3)7(2)17(12(13)22)27(23,24)25/h6-8H,4-5,14H2,1-3H3,(H,15,18)(H,16,19)(H,20,21)(H,23,24,25)/t6?,7-,8+,13-/m1/s1
InChI Key KBXJJUKRJUEIMJ-FCWTXDKESA-N
Antibiotic Activity Spectrum Gram-positive bacteria
Density 1.57 g/cm3
1. MM 42842, a new member of the monobactam family produced by Pseudomonas cocovenenans. I. Identification of the producing organism
M N Gwynn, S J Box, A G Brown, M L Gilpin J Antibiot (Tokyo). 1988 Jan;41(1):1-6. doi: 10.7164/antibiotics.41.1.
A bacterial soil isolate designated 326-32B produces a new member of the monobactam series of antibiotics, MM 42842, and the bulgecins. Identification studies show isolate 326-32B to be a strain of Pseudomonas cocoveneans which is a species previously noted for the production of toxoflavin. A description of P. cocovenenans does not appear to have been previously published and the identify of strain 326-32B was established by means of a direct comparison with the deposited organism P. cocovenenans NCIB 9450. The properties of strain 326-32B, and P. cocovenenans NCIB 9450 were compared with those of the monobactam and bulgecin producing organisms Pseudomonas acidophila ATCC 31363 and Pseudomonas mesoacidophila ATCC 31433. The four organisms were found to share certain properties, including the ability to grow at pH 4.0.
2. MM 42842, a new member of the monobactam family produced by Pseudomonas cocovenenans. II. Production, isolation and properties of MM 42842
S J Box, A G Brown, M L Gilpin, M N Gwynn, S R Spear J Antibiot (Tokyo). 1988 Jan;41(1):7-12. doi: 10.7164/antibiotics.41.7.
A new member of the monobactam family of beta-lactam antibiotics, designated MM 42842, has been detected in a culture of Pseudomonas cocovenenans. The production, isolation and some properties of the antibiotic are described. Structural studies show MM 42842 to be closely related to the previously described antibiotic sulfazecin.

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