N-(4-Aminobenzenesulfonyl) Sulfamethoxazole
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| Category | Bioactive by-products |
| Catalog number | BBF-04318 |
| CAS | 135529-16-7 |
| Molecular Weight | 408.45 |
| Molecular Formula | C16H16N4O5S2 |
| Purity | ≥90% |
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Description
A novel antibacterial analogue of the sulfonamide antibiotic, Sulfamethoxazole.
Specification
| Synonyms | Sulfamethoxazole EP Impurity B; Sulfamethoxazole Related Compound B; 4-Amino-N-[4-[[(5-methyl-3-isoxazolyl)amino]sulfonyl]phenyl]benzenesulfonamide |
| Storage | Store at 2-8°C |
| IUPAC Name | 4-amino-N-[4-[(5-methyl-1,2-oxazol-3-yl)sulfamoyl]phenyl]benzenesulfonamide |
| Canonical SMILES | CC1=CC(=NO1)NS(=O)(=O)C2=CC=C(C=C2)NS(=O)(=O)C3=CC=C(C=C3)N |
| InChI | InChI=1S/C16H16N4O5S2/c1-11-10-16(18-25-11)20-27(23,24)15-8-4-13(5-9-15)19-26(21,22)14-6-2-12(17)3-7-14/h2-10,19H,17H2,1H3,(H,18,20) |
| InChI Key | ULRBBWWPWOJYFE-UHFFFAOYSA-N |
Properties
| Appearance | White to Off-white Solid |
| Antibiotic Activity Spectrum | Bacteria |
| Boiling Point | 659.4±65.0°C (Predicted) |
| Melting Point | >228°C (dec.) |
| Density | 1.557±0.06 g/cm3 (Predicted) |
| Solubility | Slightly soluble in DMSO, Methanol |
Reference Reading
1. Heterogeneous Fenton system driven by iron-loaded sludge biochar for sulfamethoxazole-containing wastewater treatment
Liheng Liu, Ronghao Yu, Shixiong Zhao, Xingfeng Cao, Xuehong Zhang, Shaoyuan Bai J Environ Manage. 2023 Feb 25;335:117576. doi: 10.1016/j.jenvman.2023.117576. Online ahead of print.
In this study, the treatment performance of a heterogeneous Fenton system (Fe-BC + H2O2) driven by iron-loaded sludge biochar (Fe-BC) on wastewater containing sulfamethoxazole (SMX) was investigated using the CODcr removal efficiency (φ) as an indicator. The batch experimental results showed that the optimal operating conditions were as follow: initial pH 3, H2O2 concentration 20 mmol L-1, Fe-BC dose 1.2 g L-1, temperature 298 K. The corresponding φ was as high as 83.43%. The removal of CODcr was better described by BMG model and revised BMG (BMGL) model. According to the BMGL model, the φmax could be 98.37% (298 K). Moreover, the removal of CODcr was a diffusion-controlled process, while liquid film diffusion and intraparticle diffusion together determined its removal rate. The removal of CODcr should be a synergistic effect of adsorption and Fenton oxidation (real heterogeneous Fenton and homogeneous Fenton) and other pathways. Their contributions were 42.79%, 54.01% and 3.20%, respectively. For homogeneous Fenton, there seemed to be two simultaneous SMX degradation pathways: SMX→4-(pyrrolidine-11-sulfonyl)-aniline→N-(4-aminobenzenesulfonyl) acetamide/4-amino-N-ethyl benzene sulfonamides→4-amino-N-hydroxy benzene sulfonamides; SMX→N-ethyl-3-amino benzene sulfonamides→4-methanesulfonylaniline. In summary, Fe-BC had potential for practical application as a heterogeneous Fenton catalyst.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
