Catalog number:
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
It is produced by the strain of Nocardia sp. C-15003(N-1). It has the function of anti-tumor, anti-plant pathogenic fungi, skin fungi and protozoa, and has no antibacterial activity.
- Specification
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| Catalog Number | BBF-02600 |
| CAS | 72877-50-0 |
| Description | (−)-Neplanocin A potently and irreversibly inactivates SAH hydrolase (Ki = 8.39 nM). It has antitumor activity against mouse leukemia L1210 cells and broad-spectrum antiviral activity. Neplanocin A is more potent against vesicular stomatitis than the reversible SAH hydrolase inhibitor 3-deazaneplanocin (ID50 = 0.07 and 0.3 μg/ml, respectively). |
| Molecular Formula | C11H13N5O3 |
| Molecular Weight | 263.25 |
| Antibiotic Activity Spectrum | neoplastics (Tumor); fungi; viruses |
| Synonyms | NPC-A; (-)-9-(trans-2,trans-3-Dihydroxy-4-(hydroxymethyl)-cyclopent-4-enyl)-adenine; 5-(6-Amino-purin-9-yl)-3-hydroxymethyl-cyclopent-3-ene-1,2-diol |
| IUPAC Name | (1S,2R,5R)-5-(6-aminopurin-9-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol |
| Canonical SMILES | C1=C(C(C(C1N2C=NC3=C(N=CN=C32)N)O)O)CO |
| InChI | InChI=1S/C11H13N5O3/c12-10-7-11(14-3-13-10)16(4-15-7)6-1-5(2-17)8(18)9(6)19/h1,3-4,6,8-9,17-19H,2H2,(H2,12,13,14)/t6-,8-,9+/m1/s1 |
| InChI Key | XUGWUUDOWNZAGW-VDAHYXPESA-N |
| Boiling Point | 632.6±65.0°C at 760 mmHg |
| Melting Point | 220-227°C |
| Purity | ≥98% |
| Density | 1.9±0.1 g/cm3 |
| Solubility | Soluble in DMF, DMSO |
| Appearance | Colorless Acicular Crystal |
| Storage | Store at -20°C |
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