O-Carbamoyl-D-serine
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Antibiotics |
| Catalog number | BBF-00218 |
| CAS | |
| Molecular Weight | 148.12 |
| Molecular Formula | C4H8N2O4 |
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Description
O-Carbamoyl-D-serine is an antibiotic produced by Str. polychromogenes. It can inhibit the synthesis of bacterial cell wall and has weak anti-gram-positive bacteria activity.
Properties
| Appearance | White Crystal |
| Antibiotic Activity Spectrum | Gram-positive bacteria |
| Melting Point | 211-219°C |
Reference Reading
1. Role of uricase in the triggering of germination of Bacillus fastidiosus spores
J A Salas, K Johnstone, D J Ellar Biochem J. 1985 Jul 1;229(1):241-9. doi: 10.1042/bj2290241.
The likelihood that uric acid was the only compound capable of triggering germination of Bacillus fastidiosus spores was reinforced by the finding that ureidoglycollic acid, urea, NH4Cl, 2,8-dihydroxypurine and a combination of L-alanine and O-carbamoyl-D-serine were ineffective as germinants. Uric acid-triggered germination of B. fastidiosus was prevented by a range of inhibitors that also inhibited uricase activity in dormant spore extracts. O2 uptake during germination started immediately after addition of uric acid, possibly as a consequence of the oxidation of uric acid by the enzyme uricase. Germination showed a dependence on uric acid concentration, with a relatively high Km (4-5 mM). During the first 10 min of germination of heat-activated spores there was no detectable change in the number of spore-cortex reducing groups, indicating that selective cortex hydrolysis is not involved in the trigger mechanism of germination of B. fastidiosus. On the basis of the results, a model is proposed in which re-initiation of uricase activity is the mechanism by which B. fastidiosus spores are triggered to emerge from the dormant state.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
