O-Methylviridicatin
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Category | Enzyme inhibitors |
Catalog number | BBF-04502 |
CAS | 6152-57-4 |
Molecular Weight | 251.28 |
Molecular Formula | C16H13NO2 |
Purity | ≥99% |
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Description
O-Methylviridicatin is a metabolite produced by several species of Penicillium. It blocks TNF-alpha activation of the HIV LTR in the Hela-based system, with an IC50 of 5 mM, and inhibits virus production in the OM-10.1 cell line, a model of chronic infection responsive to induction by TNF-alpha, with an IC50 of 2.5 mM.
Specification
Synonyms | 3-methoxy-4-phenyl-Carbostyril; Viridicatin methyl ester; 3-O-Methylviridicatin; O-methylviridicatin; 3-methoxy-4-phenylquinolin-2(1h)-one; 3-Methoxyviridicatin |
Storage | Store at -20°C |
IUPAC Name | 3-methoxy-4-phenyl-1H-quinolin-2-one |
Canonical SMILES | COC1=C(C2=CC=CC=C2NC1=O)C3=CC=CC=C3 |
InChI | InChI=1S/C16H13NO2/c1-19-15-14(11-7-3-2-4-8-11)12-9-5-6-10-13(12)17-16(15)18/h2-10H,1H3,(H,17,18) |
InChI Key | NDTLHHOQSHJIMX-UHFFFAOYSA-N |
Properties
Appearance | Solid |
Antibiotic Activity Spectrum | Viruses |
Boiling Point | 476.5°C at 760 mmHg |
Melting Point | 184.2°C |
Density | 1.25 g/cm3 |
Solubility | Soluble in DMSO, DMF, Ethanol, Methanol, Water |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2