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Ostreogrycin B3

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Ostreogrycin B3
Category Antibiotics
Catalog number BBF-02324
CAS 31508-69-7
Molecular Weight 882.96
Molecular Formula C45H54N8O11

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Capabilities & Facilities

Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

It is produced by the strain of Str. ostreogriseus NRRL 2558 (NCIB 8792). It has anti-gram positive bacterial activity, and Ostreogrycin A has stronger antibacterial activity than other components. Ostreogrycin A or G has synergistic antibacterial effect with each component of Ostreogrycin B. The Complex has protective effect on mice infected with bacteria by subcutaneous or oral administration.

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Synonyms Virginiamycin-S1; N-(3-Hydroxypicolinoyl)-cyclo[L-Thr*-D-Abu-L-Pro-4-(dimethylamino)-N-methyl-L-Phe-4-oxo-5-hydroxy-L-Hpr-L-phenyl-Gly-]
IUPAC Name N-[(3S,6S,12R,15S,16R,19S,22S)-3-[[4-(dimethylamino)phenyl]methyl]-12-ethyl-25-hydroxy-4,16-dimethyl-2,5,11,14,18,21,24-heptaoxo-19-phenyl-17-oxa-1,4,10,13,20-pentazatricyclo[20.4.0.06,10]hexacosan-15-yl]-3-hydroxypyridine-2-carboxamide
Canonical SMILES CCC1C(=O)N2CCCC2C(=O)N(C(C(=O)N3CC(C(=O)CC3C(=O)NC(C(=O)OC(C(C(=O)N1)NC(=O)C4=C(C=CC=N4)O)C)C5=CC=CC=C5)O)CC6=CC=C(C=C6)N(C)C)C
InChI InChI=1S/C45H54N8O11/c1-6-29-42(60)52-21-11-14-30(52)43(61)51(5)32(22-26-16-18-28(19-17-26)50(3)4)44(62)53-24-35(56)34(55)23-31(53)39(57)49-37(27-12-8-7-9-13-27)45(63)64-25(2)36(40(58)47-29)48-41(59)38-33(54)15-10-20-46-38/h7-10,12-13,15-20,25,29-32,35-37,54,56H,6,11,14,21-24H2,1-5H3,(H,47,58)(H,48,59)(H,49,57)/t25-,29-,30+,31+,32+,35?,36+,37+/m1/s1
InChI Key POKJDADRNGWFHI-CFZDOXMQSA-N
Antibiotic Activity Spectrum Gram-positive bacteria
Melting Point 215°C
Solubility Soluble in Methanol, Ethanol

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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