Oxamicetin
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Category | Antibiotics |
Catalog number | BBF-02326 |
CAS | 52665-75-5 |
Molecular Weight | 634.68 |
Molecular Formula | C29H42N6O10 |
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Description
Oxamicetin is produced by the strain of Arthrobacter oxamicetus B 302-B 75. It's a nucleoside antibiotic. It has anti-bacterial, mycobacterium effects. It has protective effect on intramuscular injection in mice infected with Staphylococcus aureus and Escherichia coli, but oral administration is not effective. It inhibits pathogenic leptospirosis at 0.1-0.5 μg/mL, and inhibits non-pathogenic leptospirosis at 10-40 μg/mL.
Specification
Synonyms | 4''-Hydroxyamicetin; Antibiotic BU-1848; Oxamycetin |
IUPAC Name | 4-[[(2S)-2-amino-3-hydroxy-2-methylpropanoyl]amino]-N-[1-[(2R,4R,5S,6R)-5-[(2R,3R,4S,5S,6R)-5-(dimethylamino)-3,4-dihydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]-2-oxopyrimidin-4-yl]benzamide |
Canonical SMILES | CC1C(C(C(C(O1)OC2C(OC(CC2O)N3C=CC(=NC3=O)NC(=O)C4=CC=C(C=C4)NC(=O)C(C)(CO)N)C)O)O)N(C)C |
InChI | InChI=1S/C29H42N6O10/c1-14-21(34(4)5)22(38)23(39)26(44-14)45-24-15(2)43-20(12-18(24)37)35-11-10-19(33-28(35)42)32-25(40)16-6-8-17(9-7-16)31-27(41)29(3,30)13-36/h6-11,14-15,18,20-24,26,36-39H,12-13,30H2,1-5H3,(H,31,41)(H,32,33,40,42)/t14-,15-,18-,20-,21-,22+,23-,24-,26-,29+/m1/s1 |
InChI Key | UWVPICJGEAEOKF-OBFBSDRYSA-N |
Properties
Appearance | Crystal |
Antibiotic Activity Spectrum | Gram-positive bacteria; Gram-negative bacteria; Mycobacteria |
Melting Point | 176-179°C |
Density | 1.51 g/cm3 |
Solubility | Soluble in Hydrochloric acid, Sodium hydroxide |
Reference Reading
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2