Oxantel pamoate
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| Category | Others |
| Catalog number | BBF-03933 |
| CAS | 68813-55-8 |
| Molecular Weight | 604.65 |
| Molecular Formula | C36H32N2O7 |
| Purity | 98% |
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Description
Oxantel Pamoate is used as an anthelmintic. It has typically been used in human and animal field as a standard treatment for intestinal worms. It may be used as a fumarate reductase inhibitor to kill the bacteria responsible for periodontal disease.
Specification
| Related CAS | 36531-26-7 (free base) |
| Synonyms | (E)-3-(2-(1-methyl-1,4,5,6-tetrahydropyrimidin-2-yl)vinyl)phenol 4,4'-methylenebis(3-hydroxy-2-naphthoate); 4,4'-Methylenebis[3-hydroxy-2-naphthalenecarboxylic Acid 3-[(1E)-2-(1,4,5,6-Tetrahydro-1-methyl-2-pyrimidinyl)ethenyl]phenol; Oxantel Ebonate; Telopar |
| Storage | Store at -20°C, Under Inert Atmosphere |
| IUPAC Name | 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid;3-[(E)-2-(1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)ethenyl]phenol |
| Canonical SMILES | OC1=CC=CC(/C=C/C2=NCCCN2C)=C1.O=C(C3=C(O)C(CC4=C5C=CC=CC5=CC(C(O)=O)=C4O)=C6C=CC=CC6=C3)O |
| InChI | InChI=1/C23H16O6.C13H16N2O/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-15-9-3-8-14-13(15)7-6-11-4-2-5-12(16)10-11/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2,4-7,10,16H,3,8-9H2,1H3/b;7-6+ |
| InChI Key | CCOAINFUFGBHBA-UETGHTDLSA-N |
Properties
| Appearance | White to Off-white Solid |
| Application | Antinematodal Agents |
| Boiling Point | 383.1°C at 760 mmHg |
| Melting Point | >247°C (dec.) |
| Density | 1.09 g/cm3 |
| Solubility | Soluble in DMSO (Slightly, Heated), Methanol (Slightly, Heated) |
Reference Reading
1.Helminth control in kennels: is the combination of milbemycin oxime and praziquantel a right choice?
Rinaldi L1, Pennacchio S2, Musella V3, Maurelli MP4, La Torre F5,6, Cringoli G7. Parasit Vectors. 2015 Jan 17;8:30. doi: 10.1186/s13071-015-0647-2.
BACKGROUND: Kennel dogs are at the high risk of infections with intestinal and extra-intestinal helminths. Therefore, regular parasitological surveillance, appropriate treatment strategies and high quality standard of hygiene are required to guarantee the health and welfare of kennel dogs. The aim of the present study was to evaluate the efficacy of helminth control in kennels using different broad-spectrum anthelmintics that are routinely used in canine veterinary practice. Particular attention was given to the field efficacy and ease-of-use of each product.
2.Repurposing drugs for the treatment and control of helminth infections.
Panic G1, Duthaler U1, Speich B1, Keiser J1. Int J Parasitol Drugs Drug Resist. 2014 Jul 30;4(3):185-200. doi: 10.1016/j.ijpddr.2014.07.002. eCollection 2014.
Helminth infections are responsible for a considerable public health burden, yet the current drug armamentarium is small. Given the high cost of drug discovery and development, the high failure rates and the long duration to develop novel treatments, drug repurposing circumvents these obstacles by finding new uses for compounds other than those they were initially intended to treat. In the present review, we summarize in vivo and clinical trial findings testing clinical candidates and marketed drugs against schistosomes, food-borne trematodes, soil-transmitted helminths, Strongyloides stercoralis, the major human filariases lymphatic filariasis and onchocerciasis, taeniasis, neurocysticercosis and echinococcosis. While expanding the applications of broad-spectrum or veterinary anthelmintics continues to fuel alternative treatment options, antimalarials, antibiotics, antiprotozoals and anticancer agents appear to be producing fruitful results as well.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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