Oximidine III
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Category | Antibiotics |
Catalog number | BBF-02329 |
CAS | |
Molecular Weight | 424.45 |
Molecular Formula | C23H24N2O6 |
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Capabilities & Facilities
Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
It is produced by the strain of Pseudomonas sp. QN05727. It's an anti-tumor antibiotic. It can selectively inhibit the growth of 3Y1 in rat fibroblasts with degeneration of various tumor genes. It inhibits v-H-ras-3Y1, v-src-3Y1 cells and the normal 3Y1 cells with IC50 (nmol/L) of 14, 4.5 and 140, respectively. It stops RAS-or SRC-denatured cells at G1 phase of the cell cycle and increases p21WAF1 expression.
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IUPAC Name | (Z,4E)-N-[(Z)-3-[(4S,6S,8R,9Z,11E)-17-hydroxy-2-oxo-3,7-dioxatricyclo[11.4.0.06,8]heptadeca-1(13),9,11,14,16-pentaen-4-yl]prop-1-enyl]-4-methoxyiminobut-2-enamide |
Canonical SMILES | CON=CC=CC(=O)NC=CCC1CC2C(O2)C=CC=CC3=C(C(=CC=C3)O)C(=O)O1 |
InChI | InChI=1S/C23H24N2O6/c1-29-25-14-6-12-21(27)24-13-5-9-17-15-20-19(31-20)11-3-2-7-16-8-4-10-18(26)22(16)23(28)30-17/h2-8,10-14,17,19-20,26H,9,15H2,1H3,(H,24,27)/b7-2+,11-3-,12-6-,13-5-,25-14+/t17-,19+,20-/m0/s1 |
InChI Key | AHOWOFTYCJCPEK-VYBMSKHHSA-N |
Appearance | Colorless Powder |
Antibiotic Activity Spectrum | Neoplastics (Tumor) |
Melting Point | 87-89°C |
Solubility | Soluble in Methanol |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
