Oxytetracycline hydrochloride
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Antibiotics |
| Catalog number | BBF-02664 |
| CAS | 2058-46-0 |
| Molecular Weight | 496.90 |
| Molecular Formula | C22H24N2O9.HCl |
| Purity | ≥97% |
Online Inquiry
Description
It is produced by the strain of Str. rimosus, Str. gilvus. It has anti-gram-positive bacteria, negative bacteria, mycobacterium effects. It also has inhibitory effect on mycoplasma, rickettsia, chlamydia, spirochetes and some protoplasm. It has been used clinically. It was cross-resistant to tetracycline and aureomycin, and partially resistant to chloramphenicol.
Specification
| Related CAS | 79-57-2 (free base) 6153-64-6 (dihydrate) |
| Synonyms | Biosolvomycin; Engemycin; Oxamycen; Terramycin hydrochloride; Bisolvomycin; Dalimycin; Unimycin |
| Storage | Store at 2-8°C |
| IUPAC Name | (4S,4aR,5S,5aR,6S,12aR)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride |
| Canonical SMILES | CC1(C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O.Cl |
| InChI | 1S/C22H24N2O9.ClH/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;/h4-6,12-14,17,25-26,28,30,32-33H,1-3H3,(H2,23,31);1H/t12-,13-,14+,17+,21-,22+;/m1./s1 |
| InChI Key | SVDOODSCHVSYEK-IFLJXUKPSA-N |
| Source | Streptomyces sp. |
Properties
| Appearance | Yellow Crystalline Solid |
| Application | Antibiotic substance isolated from the elaboration products of the actinomycete, Streptomyces rimosus, grown on a suitable medium. Antibacterial. |
| Antibiotic Activity Spectrum | Gram-positive bacteria; Gram-negative bacteria; Mycobacteria; Mycoplasma |
| Boiling Point | 839.6°C at 760 mmHg |
| Melting Point | 198-202°C |
| Flash Point | 461.6ºC |
| Density | 1.71 g/cm3 |
| Solubility | Soluble in Methanol, Ethanol, DMF, DMSO, Water |
Reference Reading
1.Emerging status of anaplasmosis in cattle in Hisar.
Kumar T1, Sindhu N1, Charaya G2, Kumar A2, Kumar P2, Chandratere G3, Agnihotri D1, Khurana R1. Vet World. 2015 Jun;8(6):768-71. doi: 10.14202/vetworld.2015.768-771. Epub 2015 Jun 21.
AIM: Anaplasma marginale is a rickettsial pathogen responsible for progressive anemia in ruminants leading to huge economic losses. The objectives of this cross-sectional study were to determine the prevalence of anaplasmosis and therapeutic evaluation of traditional line of treatment.
2.Occurrence and risk assessment of tetracycline antibiotics in soil from organic vegetable farms in a subtropical city, south China.
Xiang L1, Wu XL1, Jiang YN1, Yan QY1, Li YW1, Huang XP1, Cai QY2, Mo CH3. Environ Sci Pollut Res Int. 2016 Apr 4. [Epub ahead of print]
This study investigated the occurrence of tetracycline antibiotics in soils from different organic vegetable farms in Guangzhou, a subtropical city, South China and evaluated their ecological risk. Four tetracycline compounds (oxytetracycline, tetracycline, chlortetracycline, and doxycycline) were extracted ultrasonically from soil samples (n = 69), with a solid-phase extraction cleanup, and were then measured by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). The results showed that four compounds were detected in all samples, with the concentrations of the individual compounds ranging from 0.04 to 184.8 μg/kg (dry weight). The concentrations of tetracycline compounds in the soils from different vegetable farms varied greatly, but their patterns of distribution were similar. Doxycycline was the predominant compound with a mean of 21.87 μg/kg, followed by chlortetracycline. The concentrations of doxycycline and chlortetracycline in 7.
3.Isolation and molecular characterization of Salmonella spp. from chevon and chicken meat collected from different districts of Chhattisgarh, India.
Naik VK1, Shakya S1, Patyal A1, Gade NE2, Bhoomika1. Vet World. 2015 Jun;8(6):702-6. doi: 10.14202/vetworld.2015.702-706. Epub 2015 Jun 6.
AIM: The aim was to assess the prevalence of Salmonella in raw chevon and chicken meat sold in the retail meat shops situated in and around Durg, Rajnandgaon, Dhamtari, Raipur, and Bilaspur districts of Chhattisgarh. Studies were also conducted to find out the antibiotic resistance in Salmonella isolates.
4.Toxicity of OTC to Ipomoea aquatica Forsk. and to microorganisms in a long-term sewage-irrigated farmland soil.
Ma T1,2, Chen L1,3, Wu L4, Christie P1, Luo Y5. Environ Sci Pollut Res Int. 2016 Apr 16. [Epub ahead of print]
Water spinach (Ipomoea aquatic Forsk.) was selected to investigate the effects of oxytetracycline (OTC) on the toxicity of soil contaminated by long-term sewage irrigation. After acute toxicity test in petri dish at nine different OTC-spiked levels for 48 h, the germination rate was found to be generally inhibited in all treatments treated with OTC but the root elongation and activities of several antioxidant enzymes, superoxide dismutase (SOD), peroxidase (POD) and catalase (CAT) were either forward or backward stimulated to varying extent. During a 60-day sub-chronic toxicity test by means of a pot experiment, activities of SOD, POD and CAT in both the leaf and root tissue at 25 mg OTC per kg soil (dry weight) and in root tissue at 1 mg OTC per kg soil (dry weight) were significantly different than those in other treatments, which also indicated the higher sensitivity of the root. The foliar photosynthetic rate, stomatal conductance and transpiration rate were all gradually inhibited in spite of elevated water use efficiency under the pressure of the different OTC concentrations, which were highly significant different at 10 mg OTC per kg soil (dry weight).
Recommended Products
| BBF-01829 | Deoxynojirimycin | Inquiry |
| BBF-02642 | Lactonamycin | Inquiry |
| BBF-05862 | Epirubicin | Inquiry |
| BBF-00677 | 3-Amino-3-deoxy-D-glucose | Inquiry |
| BBF-00764 | Cerebroside C | Inquiry |
| BBF-01826 | Deoxymannojirimycin | Inquiry |
Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
