P-2563 III

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Category Antibiotics
Catalog number BBF-03323
CAS
Molecular Weight 341.36
Molecular Formula C12H27N3O8

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Description

P-2563 III is an antibiotic produced by Pseudomonas fluorescens P-2563. It is effective against gram-positive and gram-negative bacteria, especially against Pseudomonas.

Specification

IUPAC Name 3,6-diamino-4-((5-amino-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,5-triol

Properties

Antibiotic Activity Spectrum Gram-positive bacteria; Gram-negative bacteria
Solubility Soluble in water.

Reference Reading

1. Sorbistin, a new aminoglycoside antibiotic complex of bacterial origin. III. Structure determination
M Konishi, S Kamata, T Tsuno, K Numata, H Tsukiura J Antibiot (Tokyo). 1976 Nov;29(11):1152-62. doi: 10.7164/antibiotics.29.1152.
The structures of sorbistins A1, A2, B, C and D have been determined including stereo-chemistry. Sorbistins A1, A2 and B are composed of a 4-acyl-amino-4-deoxy-D-glucose and 1,4-diamino-1,4-dideoxy-D-sorbitol, the latter compound being hitherto undescribed in literature. Sorbistins C and D have the same aglycone of 1,4-diamino-1,4-dideoxy-D-sorbitol, which is linked with D-glucose and 4-amino-4-deoxy-D-glucose, respectively, through a glycosidic bond.

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