Pefloxacin
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Category | Antibiotics |
Catalog number | BBF-03873 |
CAS | 70458-92-3 |
Molecular Weight | 333.36 |
Molecular Formula | C17H20FN3O3 |
Purity | >98% |
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Description
Pefloxacin is a synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria. Pefloxacin inhibits the activity of microbial DNA gyrase and topoisomerase IV. This disrupts DNA replication and prevents cell division.
Specification
Related CAS | 70458-95-6 (Mesylate) 149676-40-4 (mesylate dihydrate) |
Synonyms | 1584RB; 1589 RB; EU 5306 EU-5306; Pefloxacinium |
Storage | Store at 2-8°C |
IUPAC Name | 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid |
Canonical SMILES | CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCN(CC3)C)F)C(=O)O |
InChI | InChI=1S/C17H20FN3O3/c1-3-20-10-12(17(23)24)16(22)11-8-13(18)15(9-14(11)20)21-6-4-19(2)5-7-21/h8-10H,3-7H2,1-2H3,(H,23,24) |
InChI Key | FHFYDNQZQSQIAI-UHFFFAOYSA-N |
Source | Synthetic |
Properties
Appearance | Light Yellow Powder |
Antibiotic Activity Spectrum | Gram-positive bacteria; Gram-negative bacteria |
Boiling Point | 529.1°C at 760 mmHg |
Density | 1.32 g/cm3 |
Solubility | 0.1N NaOH (10mg/mL): Clear and very faint yellow solution |
Reference Reading
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2